Names and pronunciation
(du-tet-ra-BEN-a-zeen) Austedo
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Drug reference
(du-tet-ra-BEN-a-zeen) Austedo
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Func. class.: Central monoamine- depleting agent
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USES: For the treatment of chorea associated with Huntington’s disease and tardive dyskinesia
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CONTRAINDICATIONS Hypersensitivity, hepatic disease, MAOIs
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Black Box Warning: Suicidal ideation
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DOSAGE AND ROUTES • Adult (treatment naïve; not switching from tetrabenazine): PO Initially, 6 mg/ day; increase at weekly intervals by increments of 6 mg/day to a max of 48 mg/day; doses >12 mg should be divided throughout the day • Adult (switching from tetrabenazine): PO Discontinue tetrabenazine and start deu- tetrabenazine the next day. Use 6 mg/day for patients taking tetrabenazine 12.5 mg/day
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Available forms: Tablets 6, 9, 12 mg
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• Adult (treatment naïve; not switching from tetrabenazine): PO Initially, 6 mg/ day; increase at weekly intervals by increments of 6 mg/day to a max of 48 mg/day; doses >12 mg should be divided throughout the day
PDF page 370
• Adult (switching from tetrabenazine): PO Discontinue tetrabenazine and start deu- tetrabenazine the next day. Use 6 mg/day for patients taking tetrabenazine 12.5 mg/day
PDF page 370