Drug Action
Dexamethasone has very high glucocorticoid activity and insignificant mineralocorticoid activity.
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Drug reference
Dexamethasone has very high glucocorticoid activity and insignificant mineralocorticoid activity.
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Local inflammation of joints ▶BY INTRA-ARTICULAR INJECTION ▶Adult: 0.3–3.3 mg, where appropriate, dose may be repeated at intervals of 3–21 days according to response, dose given according to size—consult product literature Local inflammation of soft tissues ▶BY LOCAL INFILTRATION ▶Adult: 1.7–5 mg, dose given according to size—consult product literature, where appropriate may be repeated at intervals of 3–21 days, use the 3.3 mg/mL injection preparation for this dose
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Dexamethasone 3.8 mg/mL Injection has replaced dexamethasone 4 mg/mL Injection. All dosage recommendations for intravenous, intramuscular, intrarticular use or local infiltration; are given in units of dexamethasone base.
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→Appendix 1: corticosteroids
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Dexamethasone readily crosses the placenta.
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There can be variation in the licensing of different medicines containing the same drug. Solution for injection CAUTIONARY AND ADVISORY LABELS 10 ▶Dexamethasone (Non-proprietary) Dexamethasone (as Dexamethasone sodium phosphate) 3.3 mg per 1 ml Dexamethasone (base) 6.6mg/2ml solution for injection ampoules | 10 ampoule P £22.00 DT = £22.00 Dexamethasone (base) 6.6mg/2ml solution for injection vials | 5 vial P £24.00 DT = £24.00 Dexamethasone (base) 3.3mg/1ml solution for injection ampoules | 5 ampoule P £12.00 | 10 ampoule P £15.00–£23.66 DT = £23.66 Dexamethasone (as Dexamethasone sodium phosphate) 3.8 mg per 1 ml Dexamethasone (base) 3.8mg/1ml solution for injection vials | 10 vial P £19.99 DT = £20.00 (Hospital only) | 10 vial P £19.99–£20.00 DT = £20.00 eiiii F 709
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0.3–3.3 mg, where appropriate, dose may be
First-line fragment. Read the complete Indications and Dose section above.
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1.7–5 mg, dose given according to size—consult
First-line fragment. Read the complete Indications and Dose section above.
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