Names and pronunciation
(dex-a-meth′a-sone) Dextenza, Dexycu, Maxidex, Ozurdex
PDF page 373
Loading InternPractice…
Drug reference
(dex-a-meth′a-sone) Dextenza, Dexycu, Maxidex, Ozurdex
PDF page 373
Func. class.: Ophthalmic antiinflam- matory
PDF page 373
Chem. class.: Corticosteroid
PDF page 373
Do not confuse: dexamethasone/desoximetasone
PDF page 373
ACTION: Exact mechanism of antiin- flammatory action unknown; inhibits multiple inflammatory cytokines; decreases inflammation, collagen depos- its, capillary dilation, edema
PDF pages 373, 374
USES: Treatment of corticosteroid- responsive ophthalmic disorders
PDF page 374
CONTRAINDICATIONS: Hyper- sensitivity to this product or sulfites, ocular TB, acute herpes simplex (super- ficial), fungal/viral infections of the eye, posterior lens capsule rupture Precautions: Corneal infected abra- sions, glaucoma, pregnancy, breastfeed- ing, migration of intravitreal implant risk, children
PDF page 374
SIDE EFFECTS EENT: Burning, stinging, poor vision, corneal ulcerations, increased IOP, optic nerve damage
PDF page 374
DOSAGE AND ROUTES Corticosteroid-responsive ophthalmic disorders • Adult: Instill 1 or 2 drops of 0.1% ophthalmic solution or suspension every hour during the day and every 2 hr at night; reduce application to every 4 hr after response occurs
PDF page 374
Available forms: Ophthalmic solution, suspension 0.1%; implant, intravitreal (0.7 mg); insert, opthalmic 0.4 mg; intraocular suspension 9%
PDF page 374
Administer: • For ophthalmic use only • Instruct patient on proper instillation of eye ointment or solution; do not touch the tip of the dropper to the eye, finger- tips, or other surface; wait ≥15 min be- fore inserting soft contact lens
PDF page 374
Assess: • Corneal effects: ulcerations, infec- tions can worsen with this product
PDF page 374
Evaluate: • Decreased corneal inflammation
PDF page 374
CLINICAL CONSIDERATIONS
PDF page 374
Patient and caregiver information: • How to use products • Not to share with others or use for other conditions • To notify prescriber immediately if vi- sion changes or if condition worsens • To take as prescribed
PDF page 374
• Adult: Instill 1 or 2 drops of 0.1% ophthalmic solution or suspension every hour during the day and every 2 hr at night; reduce application to every 4 hr after response occurs
PDF page 374