▶Common or very common Abdominal pain
▶Uncommon Apathy (in children). asthma. chills.
drowsiness (very common in children). dry throat (in
children). extensive swelling of vaccinated limb (very
common in children). oral herpes. pain. paraesthesia.
sleep disorder (in children)
▶Frequency not known Angioedema. asthenia. hypotonic-
hyporesponsiveness episode. seizure
SIDE-EFFECTS, FURTHER INFORMATION The incidence of
local and systemic reactions is lower with acellular
pertussis vaccines than with whole-cell pertussis vaccines
used previously.
Compared with primary vaccination, injection site
reactions are more common with booster doses of vaccines
containing acellular pertussis.
Public Health England has advised (2016) that the
vaccine should not be withheld from children with a
history to a preceding dose of: fever, irrespective of
severity; hypotonic-hyporesonsive episodes; persistent
crying or screaming for more than 3 hours; severe local
reaction, irrespective of extent.
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Contra-indicated in pregnant women with a
history of encephalopathy of unknown origin within 7 days
of previous immunisation with a pertussis-containing
vaccine. Contra-indicated in pregnant women with a
history of transient thrombocytopenia or neurological
complications following previous immunisation against
diphtheria or tetanus.
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