Treatment and peri-operative prophylaxis of
haemorrhage in patients with congenital deficiency of
factors II,VII, IX, or X if purified specific coagulation
factors not available | Treatment and peri-operative
prophylaxis of haemorrhage in patients with acquired
deficiency of factors II,VII, IX, or X (e.g. during warfarin
treatment)
▶BY INTRAVENOUS INFUSION
▶Adult: (consult haematologist)
Major bleeding in patients on warfarin following
phytomenadione (initiated under specialist supervision)
▶BY INTRAVENOUS INFUSION
▶Adult: 25–50 units/kg
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History of heparin induced
thrombocytopenia. myocardial infarction within the last
3 months (no information available). unstable angina
within the last 3 months (no information available)
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Disseminated intravascular coagulation.
history of myocardial infarction or coronary heart disease.
postoperative use. risk of thrombosis. vaccination against
hepatitis A and hepatitis B may be required
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Dried
prothrombin complex is prepared from human plasma by a
suitable fractionation technique, and contains factor IX,
together with variable amounts of factors II, VII, and X.
Available from CSL Behring (Beriplex ® P/N),
Octapharma (Octaplex ®).
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