Drug reference
Treatment of acute migraine ▶BY MOUTH ▶Adult: 40 mg, followed by 40 mg after 2 hours if required, dose to be taken only if migraine recurs (patient not responding to initial dose should not take second dose for same attack); increased if necessary to 80 mg, dose to be taken for subsequent attacks if 40 mg dose inadequate; maximum 80 mg per day l UNLICENSED USE Not licensed for use in elderly.
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Arrhythmias. coronary vasospasm. heart failure. ischaemic heart disease. peripheral vascular disease. previous cerebrovascular accident. previous myocardial infarction. previous transient ischaemic attack . Prinzmetal’s angina. severe hypertension. uncontrolled hypertension
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Conditions which predispose to coronary artery disease. elderly
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→Appendix 1: eletriptan
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▶Common or very common Arrhythmias. asthenia. chest discomfort. chills. dizziness. drowsiness. dry mouth. feeling hot. flushing. gastrointestinal discomfort. headache. hyperhidrosis. increased risk of infection. muscle complaints. muscle tone increased. muscle weakness. nausea. pain. palpitations. sensation abnormal. throat tightness. vertigo ▶Uncommon Agitation. appetite decreased. arthralgia. arthritis. confusion. depersonalisation. depression. diarrhoea. dyspnoea. ear pain. eye pain. insomnia. lacrimation disorder. malaise. mood altered. movement disorders. oedema. oral disorders. peripheral vascular disease. respiratory disorder. skin reactions. speech disorder. stupor. taste altered. thinking abnormal. thirst. tinnitus. tremor. urinary disorders. urinary tract disorder . vision disorders. yawning ▶Rare or very rare Asthma. breast pain. burping. conjunctivitis. constipation. gastrointestinal disorders. hyperbilirubinaemia. lymphadenopathy. menorrhagia. myopathy. shock. voice alteration ▶Frequency not known Coronary vasospasm. hypertension. myocardial infarction. myocardial ischaemia. serotonin syndrome. stroke. syncope. vomiting SIDE-EFFECTS, FURTHER INFORMATION Discontinue if symptoms of heat, heaviness, pressure or tightness (including throat and chest) occur.
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There is limited experience of using 5HT1- receptor agonists during pregnancy; manufacturers advise that they should be avoided unless the potential benefit outweighs the risk.
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Present in milk—avoid breast-feeding for 24 hours.
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Manufacturer advises avoid in severe impairment.
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Avoid if eGFR less than 30 mL/minute/1.73 m2. Dose adjustments Reduce initial dose to 20 mg; maximum 40 mg in 24 hours.
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There can be variation in the licensing of different medicines containing the same drug. Nervous system Tablet CAUTIONARY AND ADVISORY LABELS 3 ▶Relpax (Upjohn UK Ltd) Eletriptan (as Eletriptan hydrobromide) 20 mg Relpax 20mg tablets | 6 tablet P £22.50 DT = £22.50 Eletriptan (as Eletriptan hydrobromide) 40 mg Relpax 40mg tablets | 6 tablet P £22.50 DT = £22.50
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40 mg, followed by 40 mg after 2 hours if
First-line fragment. Read the complete Indications and Dose section above.
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