Drug reference

Emtricitabine with rilpivirine and tenofovir disoproxil

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 710

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

HIV infection in patients with plasma HIV-1 RNA concentration less than 100 000 copies/mL ▶BY MOUTH ▶Adult: 1 tablet once daily

PDF page 710

Safety

Interactions

→Appendix 1: rilpivirine. tenofovir disoproxil

PDF page 710

Hepatic Impairment

Manufacturer advises caution in moderate impairment (increased risk of hepatic side- effects); avoid in severe impairment (no information available).

PDF page 710

Renal Impairment

Avoid Eviplera ® if eGFR less than 50 mL/minute/1.73 m2.

PDF page 710

Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Tablet CAUTIONARY AND ADVISORY LABELS 21, 25 ▶Eviplera (Gilead Sciences International Ltd) Rilpivirine (as Rilpivirine hydrochloride) 25 mg, Emtricitabine 200 mg,Tenofovir disoproxil (as Tenofovir disoproxil fumarate) 245 mg Eviplera 200mg/25mg/245mg tablets | 30 tablet P £525.95

PDF page 710

Clinical care

Patient And Carer Advice

Patients or carers should be given advice on how to administer Eviplera ®. Missed doses If a dose is more than 12 hours late, the missed dose should not be taken and the next dose should be taken at the normal time.

PDF page 710

Dose text by age group

Adult

1 tablet once daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 710

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Emtricitabine with rilpivirine and tenofovir disoproxil

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 710

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

HIV infection in patients with plasma HIV-1 RNA concentration less than 100 000 copies/mL ▶BY MOUTH ▶Adult: 1 tablet once daily

PDF page 710

Safety

Interactions

→Appendix 1: rilpivirine. tenofovir disoproxil

PDF page 710

Hepatic Impairment

Manufacturer advises caution in moderate impairment (increased risk of hepatic side- effects); avoid in severe impairment (no information available).

PDF page 710

Renal Impairment

Avoid Eviplera ® if eGFR less than 50 mL/minute/1.73 m2.

PDF page 710

Dose and formulations

Medicinal Forms

PDF page 710

Clinical care

Patient And Carer Advice

PDF page 710

Dose text by age group

Adult

1 tablet once daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 710

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.