Indications And Dose
Hypertension ▶BY MOUTH ▶Adult: Initially 5 mg once daily, lower initial doses may be required when used in addition to diuretic or in renal impairment; maintenance 20 mg once daily; maximum 40 mg per day Heart failure ▶BY MOUTH ▶Adult (under close medical supervision): Initially 2.5 mg once daily, increased if tolerated to 10–20 mg twice daily, dose to be increased gradually over 2–4 weeks Prevention of symptomatic heart failure in patients with asymptomatic left ventricular dysfunction ▶BY MOUTH ▶Adult (under close medical supervision): Initially 2.5 mg once daily, increased if tolerated to 10–20 mg twice daily, dose to be increased gradually over 2–4 weeks
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