Drug reference
Management of cluster headache ▶BY MOUTH USING TABLETS Nervous system ▶Adult: 1 mg once daily for 6 nights in 7; occasionally given for 1–2 weeks, dose to be taken at night l UNLICENSED USE Not licensed for the management of cluster headache.
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Acute porphyrias p. 1120. coronary heart disease. hyperthyroidism. inadequately controlled hypertension. obliterative vascular disease. peripheral vascular disease. Raynaud’s syndrome. sepsis. severe hypertension. temporal arteritis
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Anaemia. cardiac disease. dependence. elderly . risk of peripheral vasospasm
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→Appendix 1: ergotamine
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▶Common or very common Abdominal pain. dizziness. nausea. vomiting ▶Uncommon Cyanosis. diarrhoea. muscle weakness. pain in extremity. sensation abnormal. vasoconstriction ▶Rare or very rare Arrhythmias. cardiac valve fibrosis. dyspnoea. ergot poisoning (including absence of pulse and numbness in extremities). gangrene. intestinal ischaemia . myalgia. myocardial infarction. myocardial ischaemia. skin reactions ▶Frequency not known Anxiety. arthralgia. blood disorder. cerebral ischaemia. confusion. constipation. depression. drowsiness. dry mouth. extrapyramidal symptoms. hallucination. renal artery spasm. seizure. sleep disorder. thrombosis. tremor. urinary retention. vision blurred
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Avoid; oxytocic effect on the uterus.
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Avoid; ergotism may occur in infant; repeated doses may inhibit lactation.
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Avoid in severe impairment—risk of toxicity increased.
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Avoid; risk of renal vasoconstriction.
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No licensed medicines listed.
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Peripheral vasospasm Warn patient to stop treatment immediately if numbness or tingling of extremities develops and to contact doctor. l LESS SUITABLE FOR PRESCRIBING Ergotamine tartrate is less suitable for prescribing.
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1 mg once daily for 6 nights in 7; occasionally
First-line fragment. Read the complete Indications and Dose section above.
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