Drug reference

Exemestane

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1028

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

Adjuvant treatment of oestrogen-receptor-positive early breast cancer in postmenopausal women following 2–3 years of tamoxifen therapy | Advanced breast cancer in postmenopausal women in whom anti-oestrogen therapy has failed ▶BY MOUTH ▶Adult: 25 mg daily

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Contra Indications

Not indicated for premenopausal women

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Safety

Interactions

→Appendix 1: exemestane

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Side Effects

▶Common or very common Alopecia. appetite decreased. arthralgia. asthenia. bone fracture. carpal tunnel syndrome. constipation. depression. diarrhoea. dizziness . gastrointestinal discomfort. headache. hot ﬂush. hyperhidrosis. insomnia. leucopenia. nausea. osteoporosis. pain. paraesthesia. peripheral oedema. skin reactions. thrombocytopenia. vomiting ▶Rare or very rare Acute generalised exanthematous pustulosis (AGEP). drowsiness. hepatic disorders

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Pregnancy

Avoid.

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Breast Feeding

Avoid.

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Hepatic Impairment

Manufacturer advises caution.

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Renal Impairment

Manufacturer advises caution.

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Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Tablet CAUTIONARY AND ADVISORY LABELS 21 ▶Exemestane (Non-proprietary) Exemestane 25 mg Exemestane 25mg tablets | 30 tablet P £88.80 DT = £6.64 ▶Aromasin (Pfizer Ltd) Exemestane 25 mg Aromasin 25mg tablets | 30 tablet P £88.80 DT = £6.64

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Dose text by age group

Adult

25 mg daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1028

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Exemestane

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1028

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

PDF page 1028

Contra Indications

Not indicated for premenopausal women

PDF page 1028

Safety

Interactions

→Appendix 1: exemestane

PDF page 1028

Side Effects

PDF page 1028

Pregnancy

Avoid.

PDF page 1028

Breast Feeding

Avoid.

PDF page 1028

Hepatic Impairment

Manufacturer advises caution.

PDF page 1028

Renal Impairment

Manufacturer advises caution.

PDF page 1028

Dose and formulations

Medicinal Forms

PDF page 1028

Dose text by age group

Adult

25 mg daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1028

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.