Drug reference

Factor VIIa (recombinant)

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 141

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

Cardiovascular system Treatment and prophylaxis of haemorrhage in patients with haemophilia A or B with inhibitors to factors VIII or IX, acquired haemophilia, factor VII deficiency, or Glanzmann’s thrombasthenia ▶BY INTRAVENOUS INJECTION ▶Adult: (consult haematologist)

PDF page 141

Cautions

Disseminated intravascular coagulation. risk of thrombosis

PDF page 141

Safety

Side Effects

▶Uncommon Embolism and thrombosis. fever. hepatic disorders. intestinal ischaemia. skin reactions ▶Rare or very rare Angina pectoris. cerebrovascular insufﬁciency. coagulation disorders. headache. myocardial infarction. nausea. peripheral ischaemia ▶Frequency not known Angioedema. ﬂushing

PDF page 141

Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Powder and solvent for solution for injection ▶NovoSeven (Novo Nordisk Ltd) Eptacog alfa activated 50000 unit NovoSeven 1mg (50,000units) powder and solvent for solution for injection pre-filled syringes | 1 pre-filled disposable injection P £525.20 (Hospital only) NovoSeven 1mg (50,000units) powder and solvent for solution for injection vials | 1 vial P £525.20 (Hospital only) Eptacog alfa activated 100000 unit NovoSeven 2mg (100,000units) powder and solvent for solution for injection vials | 1 vial P £1,050.40 (Hospital only) NovoSeven 2mg (100,000units) powder and solvent for solution for injection pre-filled syringes | 1 pre-filled disposable injection P £1,050.40 (Hospital only) Eptacog alfa activated 250000 unit NovoSeven 5mg (250,000units) powder and solvent for solution for injection pre-filled syringes | 1 pre-filled disposable injection P £2,626.00 (Hospital only) NovoSeven 5mg (250,000units) powder and solvent for solution for injection vials | 1 vial P £2,626.00 (Hospital only) Eptacog alfa activated 400000 unit NovoSeven 8mg (400,000units) powder and solvent for solution for injection vials | 1 vial P £4,201.60 (Hospital only) NovoSeven 8mg (400,000units) powder and solvent for solution for injection pre-filled syringes | 1 pre-filled disposable injection P £4,201.60 (Hospital only)

PDF page 141

Dose text by age group

Adult

(consult haematologist)

First-line fragment. Read the complete Indications and Dose section above.

PDF page 141

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

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Drug reference

Factor VIIa (recombinant)

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 141

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

PDF page 141

Cautions

Disseminated intravascular coagulation. risk of thrombosis

PDF page 141

Safety

Side Effects

PDF page 141

Dose and formulations

Medicinal Forms

PDF page 141

Dose text by age group

Adult

(consult haematologist)

First-line fragment. Read the complete Indications and Dose section above.

PDF page 141

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.