Drug reference
Insomnia (short-term use) ▶BY MOUTH ▶Adult: 15–30 mg once daily, dose to be taken at bedtime, for debilitated patients, use elderly dose ▶Elderly: 15 mg once daily, dose to be taken at bedtime
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Respiratory depression
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Acute porphyrias p. 1120. hypoalbuminaemia. muscle weakness CAUTIONS, FURTHER INFORMATION ▶Paradoxical effects A paradoxical increase in hostility and aggression may be reported by patients taking benzodiazepines. The effects range from talkativeness and excitement to aggressive and antisocial acts. Adjustment of the dose (up or down) sometimes attenuates the impulses. Increased anxiety and perceptual disorders are other paradoxical effects.
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NHS restrictions Flurazepam capsules are not prescribable in NHS primary care.
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→Appendix 1: flurazepam
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▶Common or very common Taste altered ▶Rare or very rare Abdominal discomfort. skin eruption ▶Frequency not known Agranulocytosis. extrapyramidal symptoms. leucopenia. pancytopenia. suicide attempt. thrombocytopenia
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Benzodiazepines are present in milk, and should be avoided if possible during breast-feeding.
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Dose adjustments Manufacturer advises dose of 15 mg in mild to moderate impairment.
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Dose adjustments Start with small doses in severe impairment.
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There can be variation in the licensing of different medicines containing the same drug. Capsule CAUTIONARY AND ADVISORY LABELS 19 ▶Dalmane (Mylan) Flurazepam (as Flurazepam hydrochloride) 15 mg Dalmane 15mg capsules | 30 capsule P £6.73 d Flurazepam (as Flurazepam hydrochloride) 30 mg Dalmane 30mg capsules | 30 capsule P £8.63 d eiiii F 359
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15–30 mg once daily, dose to be taken at
First-line fragment. Read the complete Indications and Dose section above.
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15 mg once daily, dose to be taken at bedtime
First-line fragment. Read the complete Indications and Dose section above.
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