Drug reference

Fluticasone with vilanterol

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 301, 302

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

RELVAR ELLIPTA ® 184 MICROGRAMS/22 MICROGRAMS Prophylaxis of asthma ▶BY INHALATION OF POWDER ▶Child 12–17 years: 1 inhalation once daily ▶Adult: 1 inhalation once daily RELVAR ELLIPTA ® 92 MICROGRAMS/22 MICROGRAMS Prophylaxis of asthma ▶BY INHALATION OF POWDER ▶Child 12–17 years: 1 inhalation once daily ▶Adult: 1 inhalation once daily Chronic obstructive pulmonary disease with forced expiratory volume in 1 second < 70% of predicted ▶BY INHALATION OF POWDER ▶Adult: 1 inhalation once daily

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National Funding Access Decisions

Respiratory system Scottish Medicines Consortium (SMC) decisions ▶In adults The Scottish Medicines Consortium has advised (April 2014) that ﬂuticasone furoate/vilanterol (Relvar Ellipta ®) is accepted for restricted use within NHS Scotland in patients with severe chronic obstructive pulmonary disease with a forced expiratory volume in 1 second (FEV1) less than 50% of the predicted normal value.

PDF page 302

Safety

Interactions

→Appendix 1: beta2 agonists. corticosteroids

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Side Effects

▶Common or very common Abdominal pain. arthralgia. back pain. bone fracture. cough. dysphonia. fever. increased risk of infection. muscle spasms. oropharyngeal pain ▶Uncommon Vision blurred ▶Rare or very rare Angioedema. anxiety

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Pregnancy

Manufacturer advises use only if potential beneﬁt outweighs risk.

PDF page 301

Breast Feeding

Manufacturer advises avoid—no information available.

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Hepatic Impairment

Manufacturer advises caution. Dose adjustments Manufacturer advises maximum dose of 92 microgram/22 microgram once daily in moderate to severe impairment.

PDF page 301

Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Inhalation powder CAUTIONARY AND ADVISORY LABELS 8, 10 ▶Relvar Ellipta (GlaxoSmithKline UK Ltd) Vilanterol 22 microgram per 1 dose, Fluticasone furoate 92 microgram per 1 dose Relvar Ellipta 92micrograms/dose / 22micrograms/dose dry powder inhaler | 30 dose P £22.00 DT = £22.00 Vilanterol 22 microgram per 1 dose, Fluticasone furoate 184 microgram per 1 dose Relvar Ellipta 184micrograms/dose / 22micrograms/dose dry powder inhaler | 30 dose P £29.50 DT = £29.50 eiiii F 270

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Clinical care

Patient And Carer Advice

Patients or carers should be given advice on how to administer ﬂuticasone with vilanterol powder for inhalation. A steroid card should be provided.

PDF page 302

Dose text by age group

Child 12–17 years

1 inhalation once daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 301

Child 12–17 years

1 inhalation once daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 301

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Fluticasone with vilanterol

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 301, 302

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

PDF page 301

National Funding Access Decisions

PDF page 302

Safety

Interactions

→Appendix 1: beta2 agonists. corticosteroids

PDF page 301

Side Effects

PDF page 301

Pregnancy

Manufacturer advises use only if potential beneﬁt outweighs risk.

PDF page 301

Breast Feeding

Manufacturer advises avoid—no information available.

PDF page 301

Hepatic Impairment

Manufacturer advises caution. Dose adjustments Manufacturer advises maximum dose of 92 microgram/22 microgram once daily in moderate to severe impairment.

PDF page 301

Dose and formulations

Medicinal Forms

PDF page 302

Clinical care

Patient And Carer Advice

Patients or carers should be given advice on how to administer ﬂuticasone with vilanterol powder for inhalation. A steroid card should be provided.

PDF page 302

Dose text by age group

Child 12–17 years

1 inhalation once daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 301

Child 12–17 years

1 inhalation once daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 301

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.