Drug reference

Fluvoxamine maleate

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 406

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

Depressive illness ▶BY MOUTH ▶Adult: Initially 50–100 mg daily, dose to be taken in the evening, dose to be increased gradually, increased if necessary up to 300 mg daily, doses over 150 mg daily are given in divided doses; maintenance 100 mg daily Obsessive-compulsive disorder ▶BY MOUTH ▶Adult: Initially 50 mg daily, dose to be taken in the evening, dose is increased gradually if necessary after several weeks, increased if necessary up to 300 mg daily; maintenance 100–300 mg daily, doses over 150 mg daily are given in divided doses, if no improvement in obsessive-compulsive disorder within 10 weeks, treatment should be reconsidered

PDF page 406

Safety

Interactions

→Appendix 1: SSRIs

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Side Effects

▶Rare or very rare Hepatic function abnormal (discontinue) ▶Frequency not known Bone fracture. glaucoma. neuroleptic malignant-like syndrome. withdrawal syndrome neonatal

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Breast Feeding

Present in milk—avoid.

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Hepatic Impairment

Dose adjustments Manufacturer advises low initial dose.

PDF page 406

Renal Impairment

Dose adjustments Start with low dose.

PDF page 406

Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: oral suspension Tablet ▶Fluvoxamine maleate (Non-proprietary) Fluvoxamine maleate 50 mg Fluvoxamine 50mg tablets | 60 tablet P £20.98 DT = £17.53 Fluvoxamine maleate 100 mg Fluvoxamine 100mg tablets | 30 tablet P £20.98 DT = £17.70 ▶Faverin (Mylan) Fluvoxamine maleate 50 mg Faverin 50mg tablets | 60 tablet P £17.10 DT = £17.53 Fluvoxamine maleate 100 mg Faverin 100mg tablets | 30 tablet P £17.10 DT = £17.70 eiiii F 381

PDF page 406

Clinical care

Treatment Cessation

The dose should preferably be reduced gradually over about 4 weeks, or longer if withdrawal symptoms emerge (6 months in patients who have been on long-term maintenance treatment).

PDF page 406

Patient And Carer Advice

Driving and skilled tasks Patients should be counselled about the effects on driving and skilled tasks.

PDF page 406

Dose text by age group

Adult

Initially 50–100 mg daily, dose to be taken in the

First-line fragment. Read the complete Indications and Dose section above.

PDF page 406

Adult

Initially 50 mg daily, dose to be taken in the

First-line fragment. Read the complete Indications and Dose section above.

PDF page 406

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Fluvoxamine maleate

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 406

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

PDF page 406

Safety

Interactions

→Appendix 1: SSRIs

PDF page 406

Side Effects

▶Rare or very rare Hepatic function abnormal (discontinue) ▶Frequency not known Bone fracture. glaucoma. neuroleptic malignant-like syndrome. withdrawal syndrome neonatal

PDF page 406

Breast Feeding

Present in milk—avoid.

PDF page 406

Hepatic Impairment

Dose adjustments Manufacturer advises low initial dose.

PDF page 406

Renal Impairment

Dose adjustments Start with low dose.

PDF page 406

Dose and formulations

Medicinal Forms

PDF page 406

Clinical care

Treatment Cessation

The dose should preferably be reduced gradually over about 4 weeks, or longer if withdrawal symptoms emerge (6 months in patients who have been on long-term maintenance treatment).

PDF page 406

Patient And Carer Advice

Driving and skilled tasks Patients should be counselled about the effects on driving and skilled tasks.

PDF page 406

Dose text by age group

Adult

Initially 50–100 mg daily, dose to be taken in the

First-line fragment. Read the complete Indications and Dose section above.

PDF page 406

Adult

Initially 50 mg daily, dose to be taken in the

First-line fragment. Read the complete Indications and Dose section above.

PDF page 406

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.