Drug reference
Replacement of coagulation factors or other plasma proteins where their concentration or functional activity is critically reduced ▶BY INTRAVENOUS INFUSION ▶Adult: (consult haematologist) Major bleeding in patients on warfarin following phytomenadione (if dried prothrombin complex is unavailable) ▶Adult: 15 mL/kilogram
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Avoid use as a volume expander. IgA deficiency with confirmed antibodies to IgA
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Cardiac decompensation. pulmonary oedema. risk of thrombosis. severe protein S deficiency (avoid products with low protein S activity e.g. OctaplasLG ®). vaccination against hepatitis A and hepatitis B may be required
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Fresh frozen plasma is prepared from the supernatant liquid obtained by centrifugation of one donation of whole blood. A preparation of solvent/detergent treated human plasma (frozen) from pooled donors is available from Octapharma (OctaplasLG ®).
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▶Common or very common Skin reactions ▶Uncommon Fever. hypersensitivity. hypoxia. nausea. sensation abnormal. vomiting ▶Rare or very rare Abdominal pain. anxiety. arrhythmias. back pain. cardiac arrest. chest discomfort. chills. circulatory collapse. citrate toxicity. dizziness. dyspnoea. flushing. haemolytic anaemia. haemorrhage. hyperhidrosis. hypertension. hypotension. localised oedema. malaise. procedural complications. pulmonary oedema. respiratory disorders. thromboembolism
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There can be variation in the licensing of different medicines containing the same drug. Infusion ▶OctaplasLG (Octapharma Ltd) Human plasma proteins 57.5 mg per 1 ml OctaplasLG Blood Group A infusion 200ml bags | 1 bag P £75.00 OctaplasLG Blood Group B infusion 200ml bags | 1 bag P £75.00 OctaplasLG Blood Group AB infusion 200ml bags | 1 bag P £75.00 OctaplasLG Blood Group O infusion 200ml bags | 1 bag P £75.00 2.2 Subarachnoid haemorrhage CALCIUM-CHANNEL BLOCKERS eiiii F 168
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(consult haematologist)
First-line fragment. Read the complete Indications and Dose section above.
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15 mL/kilogram
First-line fragment. Read the complete Indications and Dose section above.
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