Drug reference

Ganirelix

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 800

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

Adjunct in the treatment of female infertility (initiated under specialist supervision) ▶BY SUBCUTANEOUS INJECTION ▶Adult: 250 micrograms once daily, dose to be administered in the morning (or each afternoon) starting on day 5 or day 6 of ovarian stimulation with gonadotrophins, continue throughout administration of gonadotrophins including day of ovulation induction (if administering in afternoon, give last dose in afternoon before ovulation induction), dose to be injected preferably into the upper leg (rotate injection sites to prevent lipoatrophy)

PDF page 800

Safety

Side Effects

▶Common or very common Skin reactions ▶Uncommon Headache. malaise. nausea ▶Rare or very rare Dyspnoea. facial swelling. hypersensitivity ▶Frequency not known Abdominal distension. ovarian hyperstimulation syndrome. pelvic pain

PDF page 800

Pregnancy

Avoid in conﬁrmed pregnancy—toxicity in animal studies.

PDF page 800

Breast Feeding

Avoid—no information available.

PDF page 800

Hepatic Impairment

Manufacturer advises avoid in moderate to severe impairment (no information available).

PDF page 800

Renal Impairment

Avoid in moderate to severe renal impairment.

PDF page 800

Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Solution for injection ▶Fyremadel (Ferring Pharmaceuticals Ltd) Ganirelix 500 microgram per 1 ml Fyremadel 250micrograms/0.5ml solution for injection pre-filled syringes | 1 pre- filled disposable injection P s PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES › GONADOTROPHIN- RELEASING HORMONES

PDF page 800

Dose text by age group

Adult

250 micrograms once daily, dose to be

First-line fragment. Read the complete Indications and Dose section above.

PDF page 800

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Ganirelix

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 800

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

PDF page 800

Safety

Side Effects

PDF page 800

Pregnancy

Avoid in conﬁrmed pregnancy—toxicity in animal studies.

PDF page 800

Breast Feeding

Avoid—no information available.

PDF page 800

Hepatic Impairment

Manufacturer advises avoid in moderate to severe impairment (no information available).

PDF page 800

Renal Impairment

Avoid in moderate to severe renal impairment.

PDF page 800

Dose and formulations

Medicinal Forms

PDF page 800

Dose text by age group

Adult

250 micrograms once daily, dose to be

First-line fragment. Read the complete Indications and Dose section above.

PDF page 800

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.