Indications And Dose
Cervical ripening prior to first trimester surgical abortion ▶BY VAGINA ▶Adult: 1 mg, dose to be inserted into posterior fornix 3 hours before surgery Second trimester abortion ▶BY VAGINA ▶Adult: 1 mg every 3 hours for maximum 5 administrations, to be inserted into posterior fornix, second course may begin 24 hours after start of treatment (if treatment fails, pregnancy should be terminated by another method) Second trimester intra-uterine death ▶BY VAGINA ▶Adult: 1 mg every 3 hours for maximum 5 administrations only, to be inserted into posterior fornix Medical termination of intra-uterine pregnancy of up to 49 days gestation following mifepristone | Medical termination of intra-uterine pregnancy of 50–63 days gestation following mifepristone ▶BY VAGINA ▶Adult: 1 mg Termination of pregnancy of 13–24 weeks gestation (in combination with a prostaglandin) following mifepristone ▶BY VAGINA ▶Adult: 1 mg every 3 hours, if abortion does not occur, 24 hours after start of treatment repeat course of gemeprost 1 mg by vagina up to max. 5 mg; follow-up visit after appropriate interval to assess vaginal bleeding recommended, careful monitoring of blood pressure and pulse essential for 3 hours after administration of gemeprost pessary (risk of profound hypotension); maximum 5 mg per course
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