Drug reference
Type 2 diabetes mellitus ▶BY MOUTH USING TABLETS ▶Adult: Initially 5 mg daily, adjusted according to response, dose to be taken with or immediately after breakfast; maximum 15 mg per day ▶Elderly: 2.5 mg daily, adjusted according to response, dose to be taken with or immediately after breakfast; maximum 15 mg per day l UNLICENSED USE Not licensed for use in breast feeding women with pre-existing diabetes. Not licensed for use in gestational diabetes.
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Avoid where possible in Acute porphyrias p. 1120
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→Appendix 1: sulfonylureas
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Appetite abnormal. bone marrow disorders . epigastric discomfort. erythema nodosum. fever. gastrointestinal disorder. hypereosinophilia. SIADH. Stevens-Johnson syndrome. taste metallic. vision disorders. weight increased
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The use of sulfonylureas in pregnancy should generally be avoided because of the risk of neonatal hypoglycaemia; however, glibenclamide can be used during the second and third trimesters of pregnancy in women with gestational diabetes.
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Glibenclamide can be used during breast-feeding in women with pre-existing diabetes.
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No licensed medicines listed. eiiii F 747
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Initially 5 mg daily, adjusted according to
First-line fragment. Read the complete Indications and Dose section above.
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2.5 mg daily, adjusted according to response,
First-line fragment. Read the complete Indications and Dose section above.
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