Indications And Dose
Prophylaxis of angina ▶BY SUBLINGUAL ADMINISTRATION USING SUBLINGUAL TABLETS ▶Adult: 1 tablet, to be administered prior to activity likely to cause angina Treatment of angina ▶BY SUBLINGUAL ADMINISTRATION USING SUBLINGUAL TABLETS ▶Adult: 1 tablet, dose may be repeated at 5 minute intervals if required; if symptoms have not resolved after 3 doses, medical attention should be sought Prophylaxis of angina ▶BY SUBLINGUAL ADMINISTRATION USING AEROSOL SPRAY ▶Adult: 400–800 micrograms, to be administered under the tongue and then close mouth prior to activity likely to cause angina Treatment of angina ▶BY SUBLINGUAL ADMINISTRATION USING AEROSOL SPRAY ▶Adult: 400–800 micrograms, to be administered under the tongue and then close mouth, dose may be repeated at 5 minute intervals if required; if symptoms have not resolved after 3 doses, medical attention should be sought Control of hypertension and myocardial ischaemia during and after cardiac surgery | Induction of controlled hypotension during surgery | Congestive heart failure | Unstable angina ▶BY INTRAVENOUS INFUSION ▶Adult: 10–200 micrograms/minute (max. per dose 400 micrograms/minute), adjusted according to response, consult product literature for recommended starting doses specific to indication Anal fissure ▶BY RECTUM USING OINTMENT ▶Adult: Apply 2.5 centimetres every 12 hours until pain stops. Max. duration of use 8 weeks, apply to anal canal, 2.5 cm of ointment contains 1.5 mg of glyceryl trinitrate DEPONIT ® Prophylaxis of angina ▶BY TRANSDERMAL APPLICATION ▶Adult: One ‘5’ or one ‘10’ patch to be applied to lateral chest wall, upper arm, thigh, abdomen, or shoulder; increase to two ‘10’ patches every 24 hours if necessary, to be replaced every 24 hours, siting replacement patch on different area MINITRAN ® Prophylaxis of angina ▶BY TRANSDERMAL APPLICATION ▶Adult: One ‘5’ patch to be applied to chest or upper arm; replace every 24 hours, siting replacement patch on different area, dose to be adjusted according to response Maintenance of venous patency (‘5’ patch only) ▶BY TRANSDERMAL APPLICATION ▶Adult: (consult product literature) NITRO-DUR ® Prophylaxis of angina ▶BY TRANSDERMAL APPLICATION ▶Adult: One ‘0.2mg/h’ patch to be applied to chest or outer upper arm and replaced every 24 hours, siting replacement patch on different area, dose adjusted according to response; maximum 15 mg per day PERCUTOL ® Prophylaxis of angina ▶TO THE SKIN ▶Adult: Usual dose 1–2 inches every 3–4 hours as required, to be measured on to Applirule ® and applied (usually to chest, arm, or thigh) without rubbing in and secured with surgical tape, approx. 800 micrograms/hour absorbed from 1 inch of ointment. Prophylaxis of angina (to determine dose) ▶TO THE SKIN ▶Adult: ½ inch to be administered on first day then increased by ½ inch/day until headache occurs, then reduced by ½ inch, to be measured on to Applirule ® and applied (usually to chest, arm, or thigh) without rubbing in and secured with surgical tape, approx. 800 micrograms/hour absorbed from 1 inch of ointment. TRANSIDERM-NITRO ® Prophylaxis of angina ▶BY TRANSDERMAL APPLICATION ▶Adult: One ‘5’ or one ‘10’ patch to be applied to lateral chest wall and replaced every 24 hours, siting replacement patch on different area, max. two ‘10’ patches daily Prophylaxis of phlebitis and extravasation (‘5’ patch only) ▶BY TRANSDERMAL APPLICATION ▶Adult: (consult product literature)
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