Therapeutic Action
Long-acting antipsychotic
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Drug reference
Long-acting antipsychotic
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Chronic psychosis, maintenance therapy after stabilisation with oral haloperidol
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Do not administer to patients with cardiac disorders (cardiac failure, recent myocardial infarction, conduction disorders, bradycardia, etc.), dementia (e.g. Alzheimer's disease), Parkinson's disease and history of neuroleptic malignant syndrome. Administer with caution and carefully monitor use in older patients and patients with hypokalaemia, hypotension, hyperthyroidism, renal or hepatic impairment, history of seizures. May cause: drowsiness (caution when driving/operating machinery), extrapyramidal syndrome, early or tardive dyskinesia, constipation, dry mouth, sexual dysfunction, QT-prolongation, ventricular arrhythmia, orthostatic hypotension. In case of extrapyramidal symptoms, try reducing the dose of haloperidol decanoate or, if the extrapyramidal symptoms are severe, add biperiden or trihexyphenidyl. Avoid or monitor combination with: fluoxetine, paroxetine, sertraline, promethazine, ritonavir (increased plasma concentrations of haloperidol); carbamazepine, rifampicin, phenobarbital, phenytoin (decreased plasma concentrations of haloperidol); drugs that prolong the QT interval (amiodarone, chloroquine, erythromycin, fluconazole, mefloquine, pentamidine, quinine, etc.). Avoid alcohol during treatment (increased risk of adverse effects). Avoid in women of childbearing age or offer effective contraception. Pregnancy and breastfeeding: avoid
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50 mg in 1 ml ampoule (50 mg/ml) for IM injection DO NOT ADMINISTER BY IV INJECTION.
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Adult: one injection every 3 to 4 weeks The initial dose of haloperidol decanoate corresponds to approximately 10 times the daily dose of oral haloperidol. Daily dose Monthly dose 50 mg solution oral haloperidol haloperidol decanoate IM haloperidol decanoate IM 2.5 mg 25 mg ½ amp 5 mg 50 mg 1 amp 10 mg 100 mg 2 amp 15 mg 150 mg 3 amp
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Change buttock for each injection.
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– Below 25 °C
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one injection every 3 to 4 weeks
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