Functional class
Func. class.: Corticosteroid, topical
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Drug reference
Func. class.: Corticosteroid, topical
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ACTION: Crosses cell membrane to attach to receptors to decrease inflam- mation, itching, inhibits multiple inflam- matory cytokines
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USES: Inflammation/itching in corti- costeroid-responsive dermatoses on the skin, rectal area
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CONTRAINDICATIONS: Hyper- sensitivity Precautions: Pregnancy, breastfeeding, children
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SIDE EFFECTS CNS: Seizures, increased intracranial pressure, headache CV: Hypertension EENT: Cataracts, glaucoma INTEG: Burning, folliculitis, pruritus, dermatitis, maceration MISC: Hyperglycemia, glycosuria, HPA suppression
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DOSAGE AND ROUTES Corticosteroid-responsive dermatoses, inflammation, pruritus • Adult/child: TOP apply to affected area 1 to 4 times per day Inflammation from proctitis • Adult: RECTAL 1 applicator full of foam once or twice a day × 2-3 wk, then every other day as needed; suppository: 1 bid × 2 wk
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Available forms: Hydrocortisone: cream 0.5%, 1%, 2.5%; gel 1%, 2%; lotion 0.25%, 1%, 2%, 2.5%; ointment 0.5%, 1%, 2.5%; rectal cream 1%; rectal ointment 1%; spray 1%; solution 1%, 2.5%; Hydrocortisone acetate: cream 0.5%, 1%, 2%, 2.5%; lotion 0.5%; oint- ment 0.5%, 1%; rectal foam 90 mg/ application; suppositories 25 mg, 30 Hydrocortisone butyrate: mg; cream 0.1%; ointment 0.1%; lotion; Hydrocortisone probutate: cream 0.1%; Hydrocortisone valerate: cream 0.2%, ointment 0.2%
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Administer: Topical route • May be used with dressings Cream/ointment/lotion • Apply sparingly in a thin film and rub gently
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Assess: • Skin reactions: burning, pruritus, fol- liculitis, dermatitis
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Evaluate: • Decreasing itching, inflammation on the skin, rectal area
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Patient and caregiver information: Topical route • That product may be used with dressings Cream/ointment/lotion • To apply sparingly in a thin film and rub gently into the affected area Gel • To apply sparingly in a thin film and rub gently Rectal • To remove wrapper and insert sup- pository HIGH ALERT
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PHARMACOKINETICS Unknown, minimally absorbed NURSING CONSIDERATIONS
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• Adult/child: TOP apply to affected area 1 to 4 times per day Inflammation from proctitis
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