Drug reference

Imidapril hydrochloride

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 203

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

Cardiovascular system Essential hypertension ▶BY MOUTH ▶Adult: Initially 5 mg daily, increased if necessary to 10 mg daily, dose to be taken before food, doses to be increased at intervals of at least 3 weeks; maximum 20 mg per day ▶Elderly: Initially 2.5 mg daily, increased if necessary to 10 mg daily, dose to be taken before food, doses to be increased at intervals of at least 3 weeks Essential hypertension in patients with heart failure, angina or cerebrovascular disease ▶BY MOUTH ▶Adult: Initially 2.5 mg daily, increased if necessary to 10 mg daily, dose to be taken before food, dose to be increased at intervals of at least 3 weeks; maximum 20 mg per day

PDF page 203

Safety

Interactions

→Appendix 1: ACE inhibitors

PDF page 203

Side Effects

▶Uncommon Cerebrovascular disorder. increased risk of infection. joint swelling. limb pain. oedema ▶Rare or very rare Anaemia

PDF page 203

Breast Feeding

Not recommended; alternative treatment options, with better established safety information during breast-feeding, are available.

PDF page 203

Hepatic Impairment

Imidapril is a prodrug. Manufacturer advises caution (risk of increased exposure). Dose adjustments Manufacturer advises initial dose of 2.5 mg daily.

PDF page 203

Renal Impairment

Avoid if eGFR less than 30 mL/minute/1.73 m2. Dose adjustments Initial dose 2.5 mg daily if eGFR 30–80 mL/minute/1.73 m2.

PDF page 203

Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Tablet ▶Tanatril (Mitsubishi Tanabe Pharma Europe Ltd) Imidapril hydrochloride 5 mg Tanatril 5mg tablets | 28 tablet P £6.40 DT = £6.40 Imidapril hydrochloride 10 mg Tanatril 10mg tablets | 28 tablet P £7.22 DT = £7.22 Imidapril hydrochloride 20 mg Tanatril 20mg tablets | 28 tablet P £8.67 DT = £8.67 eiiii F 179

PDF page 203

Dose text by age group

Adult

Initially 5 mg daily, increased if necessary to

First-line fragment. Read the complete Indications and Dose section above.

PDF page 203

Elderly

Initially 2.5 mg daily, increased if necessary to

First-line fragment. Read the complete Indications and Dose section above.

PDF page 203

Adult

Initially 2.5 mg daily, increased if necessary to

First-line fragment. Read the complete Indications and Dose section above.

PDF page 203

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Imidapril hydrochloride

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 203

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

PDF page 203

Safety

Interactions

→Appendix 1: ACE inhibitors

PDF page 203

Side Effects

▶Uncommon Cerebrovascular disorder. increased risk of infection. joint swelling. limb pain. oedema ▶Rare or very rare Anaemia

PDF page 203

Breast Feeding

Not recommended; alternative treatment options, with better established safety information during breast-feeding, are available.

PDF page 203

Hepatic Impairment

Imidapril is a prodrug. Manufacturer advises caution (risk of increased exposure). Dose adjustments Manufacturer advises initial dose of 2.5 mg daily.

PDF page 203

Renal Impairment

Avoid if eGFR less than 30 mL/minute/1.73 m2. Dose adjustments Initial dose 2.5 mg daily if eGFR 30–80 mL/minute/1.73 m2.

PDF page 203

Dose and formulations

Medicinal Forms

PDF page 203

Dose text by age group

Adult

Initially 5 mg daily, increased if necessary to

First-line fragment. Read the complete Indications and Dose section above.

PDF page 203

Elderly

Initially 2.5 mg daily, increased if necessary to

First-line fragment. Read the complete Indications and Dose section above.

PDF page 203

Adult

Initially 2.5 mg daily, increased if necessary to

First-line fragment. Read the complete Indications and Dose section above.

PDF page 203

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.