Drug reference
Iron-deficiency anaemia ▶BY DEEP INTRAMUSCULAR INJECTION ▶Adult: Intramuscular injection to be administered into the gluteal muscle, doses calculated according to body- weight and iron deficit (consult product literature) ▶BY SLOW INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION ▶Adult: Doses calculated according to body-weight and iron deficit (consult product literature)
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A complex of ferric hydroxide with dextran containing 5% (50 mg/mL) of iron.
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→Appendix 1: iron (injectable)
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▶Uncommon Feeling hot ▶Rare or very rare Deafness (transient). haemolysis ▶Frequency not known Injection site necrosis. rheumatoid arthritis aggravated
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Avoid in first trimester.
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Manufacturer advises avoid in decompensated cirrhosis and hepatitis.
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Avoid in acute renal failure.
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▶With intravenous use For intravenous infusion (Cosmofer ®), give intermittently in Glucose 5% or Sodium chloride 0.9%, dilute 100–200 mg in 100 mL infusion fluid; give 25mg over 15 minutes initially, then give at a rate not exceeding 6.67 mg/minute; total dose infusion diluted in 500 mL infusion fluid and given over 4–6 hours (initial dose 25 mg over 15 minutes).
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There can be variation in the licensing of different medicines containing the same drug. Solution for injection ▶CosmoFer (Pharmacosmos UK Ltd) A Iron (as Iron dextran) 50 mg per 1 ml CosmoFer 500mg/10ml solution for injection ampoules | 2 ampoule P £79.70 DT = £79.70 CosmoFer 100mg/2ml solution for injection ampoules | 5 ampoule P £39.85 DT = £39.85 eiiii F 1079
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Intramuscular injection to be administered into
First-line fragment. Read the complete Indications and Dose section above.
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Doses calculated according to body-weight and
First-line fragment. Read the complete Indications and Dose section above.
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