Drug Action
Bulk-forming laxatives relieve constipation by increasing faecal mass which stimulates peristalsis.
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Drug reference
Bulk-forming laxatives relieve constipation by increasing faecal mass which stimulates peristalsis.
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Constipation ▶BY MOUTH ▶Child 1 month–5 years: 2.5–5 mL twice daily, dose to be taken only when prescribed by a doctor, as half or whole level spoonful in water, preferably after meals, morning and evening ▶Child 6–11 years: 2.5–5 mL twice daily, dose to be given as a half or whole level spoonful in water, preferably after meals, morning and evening ▶Child 12–17 years: 1 sachet twice daily, dose to be given in water preferably after meals, morning and evening ▶Adult: 1 sachet twice daily, dose to be given in water preferably taken after food, morning and evening Constipation (dose approved for use by community practitioner nurse prescribers) ▶BY MOUTH ▶Child 6–11 years: 2.5–5 mL twice daily, dose to be given as a half or whole level spoonful in water, preferably after meals, morning and evening ▶Child 12–17 years: 1 sachet twice daily, dose to be given in water preferably after meals, morning and evening ▶Adult: 1 sachet twice daily, dose to be given in water preferably taken after food, morning and evening DOSE EQUIVALENCE AND CONVERSION ▶1 sachet equivalent to 2 level 5 ml spoonsful.
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Colonic atony. faecal impaction. intestinal obstruction. reduced gut motility. sudden change in bowel habit that has persisted more than two weeks. undiagnosed rectal bleeding
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Adequate fluid intake should be maintained to avoid oesophageal or intestinal obstruction
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Flavours of soluble granules formulations may include plain, lemon, or orange. l HANDLING AND STORAGE Ispaghula husk contains potent allergens. Individuals exposed to the product (including those handling the product) can develop hypersensitivity reactions such as rhinitis, conjunctivitis, bronchospasm and in some cases, anaphylaxis.
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Abdominal distension. bronchospasm. conjunctivitis. gastrointestinal disorders. hypersensitivity . rhinitis. skin reactions
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Dose to be taken with at least 150 mL liquid.
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There can be variation in the licensing of different medicines containing the same drug. Effervescent granules CAUTIONARY AND ADVISORY LABELS 13 EXCIPIENTS: May contain Aspartame ▶Fybogel (Reckitt Benckiser Healthcare (UK) Ltd) Ispaghula husk 3.5 gram Fybogel 3.5g effervescent granules sachets plain SF sugar-free | 30 sachet G £2.83 DT = £2.83 Fybogel Orange 3.5g effervescent granules sachets SF sugar-free | 30 sachet G £2.83 DT = £2.83 Fybogel Lemon 3.5g effervescent granules sachets SF sugar-free | 30 sachet G £2.83 DT = £2.83 ▶Fybogel Hi-Fibre (Reckitt Benckiser Healthcare (UK) Ltd) Ispaghula husk 3.5 gram Fybogel Hi-Fibre Orange 3.5g effervescent granules sachets sugar-free | 10 sachet G £2.26 sugar-free | 30 sachet G £4.85 DT = £2.83 Fybogel Hi-Fibre Lemon 3.5g effervescent granules sachets sugar-free | 10 sachet G £2.26 ▶Ispagel (Bristol Laboratories Ltd) Ispaghula husk 3.5 gram Ispagel Orange 3.5g effervescent granules sachets sugar-free | 10 sachet G £1.92 sugar-free | 30 sachet G £2.45 DT = £2.83 Granules CAUTIONARY AND ADVISORY LABELS 13 EXCIPIENTS: May contain Aspartame ▶Ispaghula husk (Non-proprietary) Ispaghula husk 3.5 gram Ispaghula husk 3.5g granules sachets gluten free | 30 sachet G £2.83 Combinations available: Senna with ispaghula husk, p. 68
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Manufacturer advises that preparations that swell in contact with liquid should always be carefully swallowed with water and should not be taken immediately before going to bed. Patients and their carers should be advised that the full effect may take some days to develop and should be given advice on how to administer ispaghula husk.
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1 sachet twice daily, dose to be given in water
First-line fragment. Read the complete Indications and Dose section above.
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1 sachet twice daily, dose to be given in water
First-line fragment. Read the complete Indications and Dose section above.
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