Drug reference

ivosidenib

Mosby’s 2024 Nursing Drug Reference

Source: Mosby’s 2024 Nursing Drug Reference
PDF pages: 733

Overview

Names and pronunciation

( I′-voh-sih′-deh-nib) Tibsovo

PDF page 733

Functional class

Func. class.: Antineoplastic

PDF page 733

Uses

USES: Relapsed or refractory AML with an isocitrate dehydrogenase-1 (IDH1) mutation

PDF page 733

Safety

Contraindications

CONTRAINDICATIONS: Hyper- sensitivity, pregnancy

PDF page 733

Warnings and precautions

Black Box Warning: Differentiation syn- drome

PDF page 733

Dose and formulations

Dosage and routes

DOSAGE AND ROUTES • Adult: PO 500 mg daily until disease progression or unacceptable toxicity HIGH ALERT

PDF page 733

Dose text by age group

Adult

• Adult: PO 500 mg daily until disease progression or unacceptable toxicity HIGH ALERT

PDF page 733

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

ivosidenib

Mosby’s 2024 Nursing Drug Reference

Source: Mosby’s 2024 Nursing Drug Reference
PDF pages: 733

Overview

Names and pronunciation

( I′-voh-sih′-deh-nib) Tibsovo

PDF page 733

Functional class

Func. class.: Antineoplastic

PDF page 733

Uses

USES: Relapsed or refractory AML with an isocitrate dehydrogenase-1 (IDH1) mutation

PDF page 733

Safety

Contraindications

CONTRAINDICATIONS: Hyper- sensitivity, pregnancy

PDF page 733

Warnings and precautions

Black Box Warning: Differentiation syn- drome

PDF page 733

Dose and formulations

Dosage and routes

DOSAGE AND ROUTES • Adult: PO 500 mg daily until disease progression or unacceptable toxicity HIGH ALERT

PDF page 733

Dose text by age group

Adult

• Adult: PO 500 mg daily until disease progression or unacceptable toxicity HIGH ALERT

PDF page 733

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.