Names and pronunciation
(kee′toe-role-ak) Acular, Acular LS, Acuvail
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Drug reference
(kee′toe-role-ak) Acular, Acular LS, Acuvail
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Func. class.: Antiinflammatory (ophthalmic)
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Chem. class.: Nonsteroidal antiinflam- matory drug (NSAID)
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ACTION: Inhibits miosis by inhibiting the biosynthesis of ocular prostaglan- dins; prostaglandins play a role in the miotic response produced during ocular K surgery by constricting the iris sphincter
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USES: Pain and inflammation after cataract surgery, refractive surgery, sea- sonal allergic conjunctivitis
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CONTRAINDICATIONS: Hyper- sensitivity to this product, NSAIDs, salicylates Precautions: Bleeding disorders, com- plicated ocular surgery, corneal denerva- tion, diabetes mellitus, rheumatoid arthritis, dry eye syndrome, pregnancy, breastfeeding, children, contact lenses
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SIDE EFFECTS CNS: Headache EENT: Abnormal sensation in eye, con- junctival hyperemia, ocular irritation, ocular pain, ocular pruritus, conjunctival hyperemia, iritis, keratitis, blurred vision, transient burning/stinging
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DOSAGE AND ROUTES Seasonal allergic conjunctivitis (Acular) • Adult/child ≥2 yr: OPHTH Instill 1 drop into affected eye qid Inflammation after cataract extraction (Acular) • Adult: OPHTH 1 drop in affected eye qid beginning 24 hr after surgery × 2 wk Corneal refracture surgery, pain, burning (Acular LS) • Adult: OPHTH 1 drop in affected eye qid × ≤4 days Cataract surgery, pain, inflammation (Acuvail) • Adult: OPHTH 1 drop bid in affected eye, starting 1 day before surgery, on the day of surgery, × 2 wk after surgery
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Available forms: Ophthalmic solution Acular (0.5%), Acular LS (0.4%), Acu- vail (0.45%)
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Administer: • Apply topically to the eye, separate by ≥5 min when using with other ophthalmics • Remove contact lenses before instilla- tion of solution • Instruct patient on proper instillation of eye solution • Do not touch the tip of the dropper to the eye, fingertips, or other surface • Do not share bottle with other patients
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Assess: • Eyes: for pain, inflammation, burning, redness after cataract surgery, visual acuity
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Evaluate: • Therapeutic response: decreased pain and inflammation after cataract surgery, refractive surgery, seasonal allergic con- junctivitis
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CLINICAL CONSIDERATIONS
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Patient and caregiver information: • To apply topically to the eye • To remove contact lenses before instil- lation of solution, wait 10 min before reinserting • Proper instillation of eye solution • Not to touch the tip of the dropper to the eye, fingertips, or other surface • Not to share bottle with other patients
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• Adult/child ≥2 yr: OPHTH Instill 1 drop into affected eye qid Inflammation after cataract extraction (Acular)
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