Drug reference

Lercanidipine hydrochloride

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 194, 195

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Drug Action

Lercanidipine is a dihydropyridine calcium- channel blocker.

PDF page 194

Indications And Dose

Mild to moderate hypertension ▶BY MOUTH ▶Adult: Initially 10 mg once daily; increased if necessary to 20 mg daily, dose can be adjusted after 2 weeks

PDF page 194

Contra Indications

Aortic stenosis. uncontrolled heart failure. unstable angina. within 1 month of myocardial infarction

PDF page 194

Cautions

Left ventricular dysfunction. sick sinus syndrome (if pacemaker not ﬁtted)

PDF page 194

Safety

Interactions

→Appendix 1: calcium channel blockers

PDF page 194

Side Effects

▶Rare or very rare Angina pectoris. asthenia. chest pain. diarrhoea. dyspepsia. urinary disorders

PDF page 194

Pregnancy

Manufacturer advises avoid—no information available.

PDF page 194

Breast Feeding

Manufacturer advises avoid.

PDF page 194

Hepatic Impairment

Manufacturer advises avoid in severe impairment.

PDF page 194

Renal Impairment

Avoid if eGFR less than 30 mL/minute/1.73 m2.

PDF page 194

Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Tablet CAUTIONARY AND ADVISORY LABELS 22 ▶Lercanidipine hydrochloride (Non-proprietary) Lercanidipine hydrochloride 10 mg Lercanidipine 10mg tablets | 28 tablet P £12.99 DT = £2.34 Lercanidipine hydrochloride 20 mg Lercanidipine 20mg tablets | 28 tablet P £15.99 DT = £2.64 ▶Zanidip (Recordati Pharmaceuticals Ltd) Lercanidipine hydrochloride 10 mg Zanidip 10mg tablets | 28 tablet P £5.70 DT = £2.34 Lercanidipine hydrochloride 20 mg Zanidip 20mg tablets | 28 tablet P £10.82 DT = £2.64 eiiii F 168

PDF pages 194, 195

Dose text by age group

Adult

Initially 10 mg once daily; increased if necessary

First-line fragment. Read the complete Indications and Dose section above.

PDF page 194

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Lercanidipine hydrochloride

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 194, 195

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Drug Action

Lercanidipine is a dihydropyridine calcium- channel blocker.

PDF page 194

Indications And Dose

Mild to moderate hypertension ▶BY MOUTH ▶Adult: Initially 10 mg once daily; increased if necessary to 20 mg daily, dose can be adjusted after 2 weeks

PDF page 194

Contra Indications

Aortic stenosis. uncontrolled heart failure. unstable angina. within 1 month of myocardial infarction

PDF page 194

Cautions

Left ventricular dysfunction. sick sinus syndrome (if pacemaker not ﬁtted)

PDF page 194

Safety

Interactions

→Appendix 1: calcium channel blockers

PDF page 194

Side Effects

▶Rare or very rare Angina pectoris. asthenia. chest pain. diarrhoea. dyspepsia. urinary disorders

PDF page 194

Pregnancy

Manufacturer advises avoid—no information available.

PDF page 194

Breast Feeding

Manufacturer advises avoid.

PDF page 194

Hepatic Impairment

Manufacturer advises avoid in severe impairment.

PDF page 194

Renal Impairment

Avoid if eGFR less than 30 mL/minute/1.73 m2.

PDF page 194

Dose and formulations

Medicinal Forms

PDF pages 194, 195

Dose text by age group

Adult

Initially 10 mg once daily; increased if necessary

First-line fragment. Read the complete Indications and Dose section above.

PDF page 194

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.