Indications And Dose
Pain in palliative care (reserved for distressed patients with severe pain unresponsive to other measures) ▶BY CONTINUOUS SUBCUTANEOUS INFUSION, OR BY INTRAMUSCULAR INJECTION, OR BY INTRAVENOUS INJECTION ▶Adult: Seek specialist advice Restlessness and confusion in palliative care ▶BY CONTINUOUS SUBCUTANEOUS INFUSION ▶Child 1–11 years: 0.35–3 mg/kg, to be administered over 24 hours ▶Child 12–17 years: 12.5–200 mg, to be administered over 24 hours ▶BY MOUTH ▶Adult: 6 mg every 2 hours as required ▶BY SUBCUTANEOUS INJECTION ▶Adult: 6.25 mg every 2 hours as required ▶BY SUBCUTANEOUS INFUSION ▶Adult: Initially 12.5–50 mg/24 hours, titrated according to response (doses greater than 100 mg/24 hours should be given under specialist supervision) Nausea and vomiting in palliative care ▶BY CONTINUOUS INTRAVENOUS INFUSION, OR BY SUBCUTANEOUS INFUSION ▶Child 1 month–11 years: 100–400 micrograms/kg, to be administered over 24 hours ▶Child 12–17 years: 5–25 mg, to be administered over 24 hours ▶BY MOUTH ▶Adult: 6 mg once daily, dose to be taken at bedtime, increased if necessary to 12.5–25 mg twice daily ▶BY SUBCUTANEOUS INJECTION ▶Adult: 6.25 mg once daily, dose to be given at bedtime, increased if necessary to 12.5–25 mg twice daily ▶BY SUBCUTANEOUS INFUSION ▶Adult: 5–25 mg/24 hours, sedation can limit the dose Schizophrenia (bed patients) ▶BY MOUTH ▶Adult: Initially 100–200 mg daily in 3 divided doses, increased if necessary to 1 g daily Schizophrenia ▶BY MOUTH ▶Adult: Initially 25–50 mg daily in divided doses, dose can be increased as necessary
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