Drug reference

Lidocaine hydrochloride

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1301, 1302

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

Dental practice ▶BY BUCCAL ADMINISTRATION USING OINTMENT ▶Adult: Rub gently into dry gum Relief of pain in oral lesions ▶TO THE LESION USING OINTMENT ▶Adult: Apply as required, rub sparingly and gently on affected areas XYLOCAINE ® Bronchoscopy | Laryngoscopy | Oesophagoscopy | Endotracheal intubation ▶TO MUCOUS MEMBRANES ▶Adult: Up to 20 doses Dental practice ▶TO MUCOUS MEMBRANES ▶Adult: 1–5 doses Maxillary sinus puncture ▶TO MUCOUS MEMBRANES ▶Adult: 3 doses Relief of pain in oral lesions ▶TO THE LESION Ear, nose and oropharynx ▶Adult: Apply thinly to the ulcer using a cotton bud l UNLICENSED USE Spray not licensed for the relief of pain in oral lesions.

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Cautions

Avoid anaesthesia of the pharynx before meals—risk of choking. can damage plastic cuffs of endotracheal tubes

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Allergy And Cross Sensitivity

▶Hypersensitivity and cross-sensitivity Hypersensitivity reactions occur mainly with the ester-type local anaesthetics, such as tetracaine; reactions are less frequent with the amide types, such as articaine, bupivacaine, levobupivacaine, lidocaine, mepivacaine, prilocaine, and ropivacaine. Cross-sensitivity reactions may be avoided by using the alternative chemical type.

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Safety

Interactions

→Appendix 1: antiarrhythmics

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Pregnancy

Crosses the placenta but not known to be harmful in animal studies—use if beneﬁt outweighs risk. When used as a local anaesthetic, large doses can cause fetal bradycardia; if given during delivery can also cause neonatal respiratory depression, hypotonia, or bradycardia after paracervical or epidural block.

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Breast Feeding

Present in milk but amount too small to be harmful.

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Hepatic Impairment

Manufacturer advises caution (risk of increased exposure).

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Renal Impairment

Possible accumulation of lidocaine and active metabolite; caution in severe impairment. l PROFESSION SPECIFIC INFORMATION Dental practitioners’ formulary Lidocaine ointment 5% may be prescribed. Spray may be prescribed as Lidocaine Spray 10% XYLOCAINE ® Dental practitioners’ formulary May be prescribed as lidocaine spray 10%.

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Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: ointment Spray ▶Xylocaine (Aspen Pharma Trading Ltd) Lidocaine 10 mg per 1 actuation Xylocaine 10mg/dose spray sugar- free | 50 ml p £6.29 DT = £6.29 Ointment ▶Lidocaine hydrochloride (Non-proprietary) Lidocaine hydrochloride 50 mg per 1 gram Lidocaine 5% ointment | 15 gram p £9.00 DT = £8.28 ANALGESICS › NON-STEROIDAL ANTI- INFLAMMATORY DRUGS

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Dose text by age group

Adult

Rub gently into dry gum

First-line fragment. Read the complete Indications and Dose section above.

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Adult

Apply as required, rub sparingly and gently on

First-line fragment. Read the complete Indications and Dose section above.

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Adult

Up to 20 doses

First-line fragment. Read the complete Indications and Dose section above.

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Adult

1–5 doses

First-line fragment. Read the complete Indications and Dose section above.

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Adult

3 doses

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1301

Adult

Apply thinly to the ulcer using a cotton bud

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1301

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Lidocaine hydrochloride

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1301, 1302

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

PDF page 1301

Cautions

Avoid anaesthesia of the pharynx before meals—risk of choking. can damage plastic cuffs of endotracheal tubes

PDF page 1301

Allergy And Cross Sensitivity

PDF page 1301

Safety

Interactions

→Appendix 1: antiarrhythmics

PDF page 1301

Pregnancy

PDF page 1301

Breast Feeding

Present in milk but amount too small to be harmful.

PDF page 1301

Hepatic Impairment

Manufacturer advises caution (risk of increased exposure).

PDF page 1301

Renal Impairment

PDF page 1301

Dose and formulations

Medicinal Forms

PDF pages 1301, 1302

Dose text by age group

Adult

Rub gently into dry gum

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1301

Adult

Apply as required, rub sparingly and gently on

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1301

Adult

Up to 20 doses

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1301

Adult

1–5 doses

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1301

Adult

3 doses

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1301

Adult

Apply thinly to the ulcer using a cotton bud

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1301

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.