Therapeutic Action
Phenicol antibacterial, with prolonged effect
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Drug reference
Phenicol antibacterial, with prolonged effect
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Treatment of meningococcal meningitis during epidemics
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Do not administer to patients with: history of allergic reaction or bone marrow depression during a previous treatment with chloramphenicol; G6PD deficiency. May cause: dose-related haematological toxicity (bone marrow depression, anaemia, leucopenia, thrombocytopenia), allergic reactions. In these events, stop treatment immediately; gastrointestinal disturbances, peripheral and optic neuropathies. Avoid or monitor combination with potentially haematotoxic drugs (carbamazepine, co- trimoxazole, flucytocine, pyrimethamine, zidovudine, etc.). Pregnancy: CONTRA-INDICATED Breast-feeding: CONTRA-INDICATED
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500 mg oily suspension in 2 ml ampoule (250 mg/ml) for IM injection only. NEVER FOR IV INJECTION.
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Child over 2 years and adult: 100 mg/kg single dose (max. 3 g per dose) Age Weight Dose Volume 2 to < 6 years 13 to < 21 kg 1.5 g 6 ml 6 to < 10 years 21 to < 31 kg 2 g 8 ml 10 to < 15 years 31 to < 54 kg 2.5 g 10 ml ≥ 15 years and adult ≥ 54 kg 3 g 12 ml If necessary, administer half the dose into each buttock.
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Single dose. If there is no improvement after 24 hours, a second dose may be administered.
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Oily chloramphenicol is not recommended as chemoprophylaxis for meningitis contacts during epidemics. Shake the injection suspension before administration.
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– Below 25 °C
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100 mg/kg single dose (max. 3 g per dose)
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