Therapeutic Action
Opioid antidiarrhoeal
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Drug reference
Opioid antidiarrhoeal
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Symptomatic treatment of persistent diarrhoea in adults with HIV infection, in combination with rehydration
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Do not exceed indicated doses. Do not administer to children. Do not administer to patients with bloody diarrhoea, ulcerative colitis, diarrhoea due to antibiotics. May cause: constipation, allergic skin reactions, drowsiness, dizziness. In the event of overdosage, treat with naloxone. Pregnancy: no contra-indication Breast-feeding: no contra-indication
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2 mg capsule or tablet
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Adult: 4 mg (2 capsules), then 2 mg (1 capsule) after each loose stool, without exceeding 16 mg daily (8 capsules daily).
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According to clinical response
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Rehydration is essential and must be adapted to the severity of diarrhoea. Loperamide is not included in the WHO list of essential medicines.
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– Below 25 °C
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4 mg (2 capsules), then 2 mg (1 capsule) after each loose stool, without exceeding 16 mg daily (8 capsules daily).
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