Therapeutic Action
H1 antihistamine
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Drug reference
H1 antihistamine
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Symptomatic treatment of minor allergic reactions (urticaria, allergic conjunctivitis, etc.)
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Administer with caution and reduce the dose (administer every other day) in patients with severe renal or hepatic impairment. May cause: headache, dizziness, drowsiness (caution when driving/operating machinery), nervousness, insomnia, increased appetite, rash. Monitor combination with: central nervous system depressants (opioid analgesics, antipsychotics, sedatives, antidepressants, etc.); erythromycin, fluconazole, fluoxetine, amiodarone, ritonavir, cimetidine (increased plasma concentrations of loratadine). Avoid alcohol during treatment (increased risk of adverse effects). Pregnancy: avoid during the first trimester (uncertain risk of hypospadias) Breast-feeding: no contra-indication
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5 mg/5 ml oral solution 10 mg tablet
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Child over 2 years and under 30 kg: 5 mg (5 ml) once daily Child over 30 kg and adult: 10 mg (1 tab) once daily
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As short as possible (a few days).
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Loratadine is less sedating than promethazine.
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– Below 25 °C
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10 mg (1 tab) once daily
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