Drug reference
Emergency treatment of acute hypotension ▶INITIALLY BY INTRAVENOUS INJECTION ▶Adult: Initially 0.5–5 mg, then (by intravenous infusion) 15–100 mg, adjusted according to response Acute hypotension ▶BY INTRAVENOUS INFUSION ▶Adult: 15–100 mg, adjusted according to response
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Cirrhosis. coronary vascular thrombosis. diabetes mellitus. elderly. extravasation at injection site may cause necrosis. following myocardial infarction. hypercapnia. hypertension. hyperthyroidism. hypoxia. mesenteric vascular thrombosis. peripheral vascular thrombosis. Prinzmetal’s variant angina. uncorrected hypovolaemia CAUTIONS, FURTHER INFORMATION ▶Hypertensive response Metaraminol has a longer duration of action than noradrenaline, and an excessive vasopressor response may cause a prolonged rise in blood pressure. Cardiovascular system
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→Appendix 1: sympathomimetics, vasoconstrictor
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▶Common or very common Headache. hypertension ▶Rare or very rare Skin exfoliation. soft tissue necrosis ▶Frequency not known Abscess. arrhythmias. nausea. palpitations. peripheral ischaemia
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May reduce placental perfusion— manufacturer advises use only if potential benefit outweighs risk.
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Manufacturer advises caution—no information available.
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Monitor blood pressure and rate of flow frequently.
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For intravenous infusion, give continuously or via drip tubing in Glucose 5% or Sodium chloride 0.9%. Suggested volume 500 mL.
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There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: solution for injection Solution for injection ▶Metaraminol (Non-proprietary) Metaraminol (as Metaraminol tartrate) 10 mg per 1 ml Metaraminol 10mg/1ml solution for injection ampoules | 10 ampoule P £30.45
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Initially 0.5–5 mg, then (by intravenous
First-line fragment. Read the complete Indications and Dose section above.
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15–100 mg, adjusted according to response
First-line fragment. Read the complete Indications and Dose section above.
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