Therapeutic Action
Antiemetic (dopamine antagonist)
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Drug reference
Antiemetic (dopamine antagonist)
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Symptomatic treatment of nausea and vomiting in adults
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Do not administer to children < 18 years and to patients with gastrointestinal haemorrhage, obstruction or perforation. Reduce the dose by half in patients with severe renal impairment. Administer with caution and monitor use in patients > 60 years and patients with epilepsy or Parkinson's disease. May cause: drowsiness (caution when driving/operating machinery), dizziness, confusion, extrapyramidal symptoms, seizures (especially in patients with epilepsy), allergic reactions; neuroleptic malignant syndrome (unexplained hyperthermia with neuromuscular disorders), exceptional but requiring immediate treatment discontinuation. Do not combine with levodopa (antagonism). Avoid combination with CNS depressants (opioid analgesics, antipsychotics, sedatives, antidepressants, antihistamines, etc.). Avoid alcohol during treatment (increased risk of adverse effects). Pregnancy: no contra-indication Breast-feeding: no contra-indication
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10 mg tablet
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Adult under 60 kg: 5 mg 3 times daily Adult over 60 kg: 10 mg 3 times daily The interval between each dose should be at least 6 hours (even in the event of vomiting).
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Max. 5 days
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– – Below 25 °C
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5 mg 3 times daily
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10 mg 3 times daily
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