Names and pronunciation
(mocks-ih-floks′a-sin) Vigamox, Moxeza
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Drug reference
(mocks-ih-floks′a-sin) Vigamox, Moxeza
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Func. class.: Ophthalmic antiinfective
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Chem. class.: Fluoroquinolone
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Do not confuse: moxifloxacin/ciprofloxacin/gatifloxacin/ levoFLOXacin
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ACTION: Inhibits DNA gyrase, thereby decreasing bacterial replication
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USES: Bacterial conjunctivitis (aero- bic gram-positive/negative organisms), Chlamydia trachomatis
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CONTRAINDICATIONS: Hyper- sensitivity to this product or fluoroquinolones Precautions: Pregnancy, breastfeeding
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SIDE EFFECTS EENT: Hypersensitivity, pruritus, blurred vision, tearing
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DOSAGE AND ROUTES Bacterial conjunctivitis • Adult/adolescent/child ≥1 yr: oph- thalmic SOL 1 drop in affected eye(s) bid (Moxeza) or tid (Vigamox) × 7 days
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Available forms: Ophthalmic solution 0.5%
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Administer: Ophthalmic route • Commercially available ophthalmic solutions are not for injection subcon- junctivally or into the anterior chamber of the eye • Apply topically to the eye, taking care to avoid contamination • Do not touch the tip of the dropper to the eye, fingertips, or other surface • Apply pressure to lacrimal sac for 1 min after instillation • Avoid wearing contact lenses during treatment
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Assess: • Allergic reaction: assess for hypersen- sitivity; discontinue product
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Evaluate: • Decreased ophthalmic infection
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CLINICAL CONSIDERATIONS
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Patient and caregiver information: Ophthalmic route • To apply topically to the eye, taking care to avoid contamination • That product is for ophthalmic use only • Not to touch the tip of the dropper to the eye, fingertips, or other surface • To apply pressure to lacrimal sac for 1 min after installation • To avoid wearing contact lenses during treatment
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PHARMACOKINETICS Half-life 13 hr
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• Adult/adolescent/child ≥1 yr: oph- thalmic SOL 1 drop in affected eye(s) bid (Moxeza) or tid (Vigamox) × 7 days
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