Names and pronunciation
(myoo-pihr′oh-sin) Bactroban , Centany, Centany AT
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Drug reference
(myoo-pihr′oh-sin) Bactroban , Centany, Centany AT
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Func. class.: Topical antiinfective
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ACTION: Antibacterial activity results from inhibition of protein synthesis; bac- teriostatic at low concentration, bacteri- cidal at high concentration
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USES: Impetigo, skin lesions (Staphylo- coccus aureus/Streptococcus pyogenes); nasal: methicillin-resistant S. aureus
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CONTRAINDICATIONS: Hyper- sensitivity to this product Precautions: Open wounds, burns, severe kidney disease, children, preg- nancy, breastfeeding
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SIDE EFFECTS CNS: Headache EENT: Burning, pharyngitis, rhinitis (nasal) GI: Taste change, nausea INTEG: Burning, rash, pruritus
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INTERACTIONS Decrease: Effect of other nasal products
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DOSAGE AND ROUTES Impetigo • Adult/child: TOP apply to affected area tid × 1-2 wk Skin lesions • Adult/child: TOP apply to affected area tid × 10 days Methicillin-resistant S. aureus in the nose • Adult/child ≥12 yr: NASAL divide oint- ment in single use tube in half; use in each nostril bid × 5 days
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Available forms: Topical cream, oint- ment 2%; intranasal ointment 2%
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Administer: Topical route • Do not use skin products near the eyes, nose, or mouth • Wash hands before and after use; wash affected area and gently pat dry • May cover treated areas with gauze dressing Cream/ointment • Apply a thin film to the cleansed af- fected area; massage gently into affected areas; do not use near eyes, mouth • Nasal: Close nostrils by squeezing and releasing and gently massaging over 1 min
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Assess: • Allergic reaction: assess for hypersen- sitivity; product may need to be discon- tinued • Infection: assess for number of le- sions, severity in impetigo, other skin disorders
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Evaluate: • Decreased lesions in impetigo, other skin disorders
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CLINICAL CONSIDERATIONS
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Patient and caregiver information: Topical route • Not to use skin products near the eyes, nose, or mouth • To wash hands before and after use and to wash affected area and gently pat dry • Cream/ointment: to apply a thin film to the cleansed affected area; to cover treated areas with gauze dressing if desired • Nasal: to close nostrils by squeezing and releasing and gently massaging over 1 min
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• Adult/child: TOP apply to affected area tid × 1-2 wk Skin lesions
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• Adult/child: TOP apply to affected area tid × 10 days Methicillin-resistant S. aureus in the nose
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• Adult/child ≥12 yr: NASAL divide oint- ment in single use tube in half; use in each nostril bid × 5 days
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