Names and pronunciation
(Nal-ox′ee-gol) Movantik
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Drug reference
(Nal-ox′ee-gol) Movantik
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Func. class.: Antidote, opioid antagonist
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USES: Treatment of opioid-induced constipation with chronic noncancer pain, including patients with chronic pain related to prior cancer or its treat- ment who do not require frequent (weekly) opioid dosage escalation
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DOSAGE AND ROUTES Adult: PO 25 mg daily, 1 hr before or 2 hr after morning meal if not tolerated, reduce to 12.5 mg daily; moderate CYP3A4 inhibitor use: 12.5 mg daily Renal dose • Adult: PO CCr <60 mL/min 12.5 mg daily, may increase to 25 mg daily if needed
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Available forms: Tablet 12.5 mg
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• Adult: PO CCr <60 mL/min 12.5 mg daily, may increase to 25 mg daily if needed
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