Drug reference
Benign gastric, duodenal or NSAID-associated ulceration ▶BY MOUTH ▶Adult: 300 mg once daily for 4–8 weeks, dose to be taken in the evening, alternatively 150 mg twice daily for 4–8 weeks; maintenance 150 mg once daily, dose to be taken at night Gastro-oesophageal reflux disease ▶BY MOUTH ▶Adult: 150–300 mg twice daily for up to 12 weeks
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Nizatidine can be sold to the public for the prevention and treatment of symptoms of food-related heartburn and meal-induced indigestion in adults and children over 16 years; max. single dose 75 mg, max. daily dose 150 mg for max. 14 days.
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→Appendix 1: H2 receptor antagonists
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▶Rare or very rare Anaemia. hyperuricaemia. serum sickness ▶Frequency not known Hyperhidrosis
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Manufacturer advises avoid unless essential.
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Amount too small to be harmful.
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Manufacturer advises caution.
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Dose adjustments Use half normal dose if eGFR 20–50 mL/minute/1.73 m2. Use one-quarter normal dose if eGFR less than 20 mL/minute/1.73 m2.
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There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: oral suspension, oral solution Capsule ▶Nizatidine (Non-proprietary) Nizatidine 150 mg Nizatidine 150mg capsules | 30 capsule P £12.20 DT = £4.54 Nizatidine 300 mg Nizatidine 300mg capsules | 30 capsule P £15.43 DT = £15.43 eiiii F 78
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300 mg once daily for 4–8 weeks, dose to be
First-line fragment. Read the complete Indications and Dose section above.
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150–300 mg twice daily for up to 12 weeks
First-line fragment. Read the complete Indications and Dose section above.
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