Indications And Dose
Endometriosis ▶BY MOUTH ▶Adult: 10–15 mg daily for 4–6 months or longer, to be started on day 5 of cycle; increased to 20–25 mg daily if required, dose only increased if spotting occurs and reduced once bleeding has stopped Dysfunctional uterine bleeding (to arrest bleeding) | Menorrhagia (to arrest bleeding) ▶BY MOUTH ▶Adult: 5 mg 3 times a day for 10 days Dysfunctional uterine bleeding (to prevent bleeding) | Menorrhagia (to prevent bleeding) ▶BY MOUTH ▶Adult: 5 mg twice daily, to be taken from day 19 to day 26 of cycle Dysmenorrhoea ▶BY MOUTH ▶Adult: 5 mg 3 times a day for 3–4 cycles, to be taken from day 5–24 of cycle Premenstrual syndrome (but not recommended) ▶BY MOUTH ▶Adult: 5 mg 2–3 times a day for several cycles, to be taken from day 19–26 of cycle Postponement of menstruation ▶BY MOUTH ▶Females of childbearing potential: 5 mg 3 times a day, to be started 3 days before expected onset (menstruation occurs 2–3 days after stopping) Breast cancer ▶BY MOUTH ▶Adult: 40 mg daily, increased if necessary to 60 mg daily Short-term contraception ▶BY DEEP INTRAMUSCULAR INJECTION ▶Females of childbearing potential: 200 mg, to be administered within first 5 days of cycle or immediately after parturition (duration 8 weeks). To be injected into the gluteal muscle, then 200 mg after 8 weeks if required Contraception ▶BY MOUTH ▶Females of childbearing potential: 350 micrograms daily, dose to be taken at same time each day, starting on day 1 of cycle then continuously, if administration delayed for 3 hours or more it should be regarded as a ‘missed pill’
PDF pages 828, 829