Names and pronunciation
(oh-lap′a-rib) Lynparza
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Drug reference
(oh-lap′a-rib) Lynparza
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Func. class.: Antineoplastic-PARP
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USES: Treatment of deleterious or sus- pected deleterious germline BRCA- mutated advanced ovarian cancer in patients who have not responded suc- cessfully to ≥3 prior courses of chemo- therapy, as monotherapy, castration- resistant prostate cancer
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DOSAGE AND ROUTES • Adult female: PO 300 mg bid, until disease progression or unacceptable tox- icity. Avoid use of concomitant strong and moderate CYP3A4 inhibitors if possible
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Available forms: Tablets 100, 150 mg HIGH ALERT
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• Adult female: PO 300 mg bid, until disease progression or unacceptable tox- icity. Avoid use of concomitant strong and moderate CYP3A4 inhibitors if possible
PDF page 978