Therapeutic Action
Analgesic, antipyretic
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Drug reference
Analgesic, antipyretic
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Mild pain Fever
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Administer with caution to patients with hepatic impairment. Reduce the dose in: children with severe acute malnutrition: 10 mg/kg up to 3 times maximum per 24 hours patients with dengue with warning sign(s): Child: 10 mg/kg 3 to 4 times daily Adult: 500 mg 3 to 4 times daily Pregnancy: no contra-indication Breast-feeding: no contra-indication
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100 mg and 500 mg tablets 100 mg dispersible tablet 120 mg/5 ml oral suspension
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Child under 1 month: 10 mg/kg 3 or 4 times daily (max. 40 mg/kg daily) Child 1 month and over: 15 mg/kg 3 or 4 times daily (max. 60 mg/kg daily) Adult: 1 g 3 or 4 times daily (max. 4 g daily) Age Weight 120 mg/5 ml susp. 100 mg tablet 500 mg tablet < 1 month < 4 kg 1.5 ml x 3 − − 1 to < 3 months 4 to < 6 kg 2.5 ml x 3 ½ tab x 3 − 3 months to < 1 year 6 to < 10 kg 4 ml x 3 1 tab x 3 − 1 to < 3 years 10 to < 15 kg 6 ml x 3 1½ tab x 3 − 3 to < 5 years 15 to < 20 kg 8 ml x 3 2 tab x 3 − 5 to < 9 years 20 to < 30 kg 12 ml x 3 3 tab x 3 − 9 to < 14 years 30 to < 50 kg – – 1 tab x 3 ≥ 14 years and adult ≥ 50 kg – – 2 tab x 3
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According to clinical response
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For mild pain, paracetamol is used alone or in combination with an NSAID. For moderate pain, paracetamol is used in combination with an NSAID and codeine or tramadol. For severe pain, paracetamol is used in combination with an NSAID and morphine. Paracetamol is particularly recommended for patients allergic to aspirin, patients with a history of gastric problems and for pregnant and breast-feeding women and children. Paracetamol has no anti-inflammatory properties. N-acetylcysteine IV is the antidote for paracetamol poisoning.
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– Below 25 °C
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10 mg/kg 3 or 4 times daily (max. 40 mg/kg daily)
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15 mg/kg 3 or 4 times daily (max. 60 mg/kg daily)
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1 g 3 or 4 times daily (max. 4 g daily)
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