Therapeutic Action
Analgesic, antipyretic
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Drug reference
Analgesic, antipyretic
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Very high fever, only when oral administration is not possible Mild pain, only when oral administration is not possible
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Do not administer to patients with severe hepatic impairment. Administer with caution to patients with moderate hepatic impairment, severe renal impairment, chronic alcoholism, malnutrition, dehydration. May cause (very rarely): malaise, hypotension and rash. Pregnancy: no contra-indication Breast-feeding: no contra-indication
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500 mg (10 mg/ml, 50 ml) and 1 g (10 mg/ml, 100 ml) vials, for infusion
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Neonate: 7.5 mg/kg (0.75 ml/kg) every 6 hours, to be administered over 15 minutes (max. 30 mg/kg daily) Child ≥ 1 month and < 10 kg: 10 mg/kg (1 ml/kg) every 6 hours, to be administered over 15 minutes (max. 30 mg/kg daily) Patient ≥ 10 kg and < 50 kg: 15 mg/kg (1.5 ml/kg) every 6 hours, to be administered over 15 minutes (max. 60 mg/kg daily) Patient ≥ 50 kg: 1 g (100 ml) every 6 hours, to be administered over 15 minutes (max. 4 g daily)
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According to clinical response. Change to oral route as soon as possible.
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As the efficacy of IV paracetamol is not superior to the efficacy of oral paracetamol, the IV route is restricted to situations where oral administration is not possible. For mild pain, IV paracetamol is used alone or in combination with an NSAID administered parenterally. For moderate pain, IV paracetamol is used in combination with an NSAID and tramadol administered parenterally. For severe pain, IV paracetamol is used in combination with an NSAID and morphine administered parenterally. Paracetamol has no anti-inflammatory properties. Do not mix with other drugs in the same infusion bottle.
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– Below 25 °C
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10 mg/kg (1 ml/kg) every 6 hours, to be administered over 15 minutes (max. 30 mg/kg daily)
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