Drug reference
Prevention and treatment of secondary hyperparathyroidism associated with chronic kidney disease ▶BY MOUTH ▶Adult: (consult product literature) Prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure in patients on haemodialysis ▶Adult: To be administered via haemodialysis access (consult product literature)
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→Appendix 1: vitamin D substances
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GENERAL SIDE-EFFECTS ▶Common or very common Electrolyte imbalance. hypoparathyroidism. taste altered ▶Uncommon Asthenia. diarrhoea. dizziness. dry mouth. malaise. muscle complaints. pain ▶Frequency not known Angioedema. laryngeal oedema SPECIFIC SIDE-EFFECTS ▶Uncommon ▶With oral use Breast tenderness. gastrointestinal discomfort. gastrooesophageal reflux disease. palpitations . peripheral oedema. pneumonia ▶With parenteral use Alopecia. anaemia. anxiety. arrhythmias. asthma. breast cancer. breast pain. cardiac arrest. cerebrovascular insufficiency. chest pain. coma. condition aggravated. confusion. conjunctivitis. cough. delirium. depersonalisation. dyspepsia. dysphagia. dyspnoea. ear disorder. erectile dysfunction. fever. gait abnormal. gastrointestinal disorders. glaucoma. haemorrhage. hirsutism. hyperhidrosis. hyperparathyroidism. hypertension. hypotension. increased risk of infection. insomnia. joint disorders. leucopenia. lymphadenopathy. myoclonus. oedema. pulmonary oedema. sensation abnormal. sepsis. syncope . weight decreased
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Manufacturer advises avoid—toxicity in animal studies.
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Manufacturer advises avoid—no information available.
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▶Monitor plasma calcium and phosphate during dose titration and at least monthly when stabilised. ▶Monitor parathyroid hormone concentration.
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There can be variation in the licensing of different medicines containing the same drug. Solution for injection EXCIPIENTS: May contain Ethanol, propylene glycol ▶Zemplar (AbbVie Ltd) Paricalcitol 5 microgram per 1 ml Zemplar 5micrograms/1ml solution for injection vials | 5 vial P £62.00 (Hospital only) Capsule EXCIPIENTS: May contain Ethanol ▶Zemplar (AbbVie Ltd) Paricalcitol 1 microgram Zemplar 1microgram capsules | 28 capsule P £69.44 DT = £69.44 Paricalcitol 2 microgram Zemplar 2microgram capsules | 28 capsule P £138.88 DT = £138.88 VITAMINS AND TRACE ELEMENTS › VITAMIN E
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(consult product literature)
First-line fragment. Read the complete Indications and Dose section above.
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To be administered via haemodialysis access
First-line fragment. Read the complete Indications and Dose section above.
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