Names and pronunciation
(pen-taz′oh-seen/nal-oks′one)
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Drug reference
(pen-taz′oh-seen/nal-oks′one)
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Func. class.: Analgesic, opioid partial agonist Controlled substance schedule: IV
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USES: Moderate to severe pain
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CONTRAINDICATIONS: Hypersensitivity
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Black Box Warning: Addiction, abuse, misuse; opioid analgesic REMS; life- threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; use with benzodi- azepines, other CNS depressants
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DOSAGE AND ROUTES Pain management • Adult: PO: 1 tablet (pentazocine 50 mg/ naloxone 0.5 mg) q3-4 hr; may increase to 2 tablets (pentazocine 100 mg/naloxone 1 mg) if needed, max 12 tablets (pentazocine 600 mg/naloxone 6 mg)/day; max 600 mg/6 mg/day
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Available forms: Tabs 50 mg/0.5 mg HIGH ALERT
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• Adult: PO: 1 tablet (pentazocine 50 mg/ naloxone 0.5 mg) q3-4 hr; may increase to 2 tablets (pentazocine 100 mg/naloxone 1 mg) if needed, max 12 tablets (pentazocine 600 mg/naloxone 6 mg)/day; max 600 mg/6 mg/day
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