Therapeutic Action
Penicillin antibacterial
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Drug reference
Penicillin antibacterial
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Streptococcal pharyngitis, scarlet fever Alternative to first-line antibiotic treatment of diphtheria Completion treatment following parenteral therapy with penicillin
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Do not administer to patients with allergy to penicillin. Administer with caution to patients with allergy to cephalosporin (cross-sensitivity may occur) or severe renal impairment (reduce dose). May cause: diarrhea, nausea; allergic reactions sometimes severe. Do not combine with methotrexate. Pregnancy: no contra-indication Breast-feeding: no contra-indication
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250 mg tablet (400 000 IU) Powder for oral suspension, 125 mg/5 ml (200 000 IU/5 ml): to be reconstituted with filtered water to be administered using a measuring device (oral syringe, measuring spoon, or cup with graduations)
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Streptococcal pharyngitis, scarlet fever 125 mg/5 ml Age Weight Daily dose 250 mg tablet oral susp. < 1 year < 10 kg 125 mg x 2 5 ml x 2 − 1 to < 6 years 10 to < 21 kg 250 mg x 2 10 ml x 2 − 6 to < 12 years 21 to < 39 kg 500 mg x 2 20 ml x 2 2 tab x 2 ≥ 12 years and ≥ 39 kg 1 g x 2 − 4 tab x 2 adult Diphtheria Child under 40 kg: 10 to 15 mg/kg (max. 500 mg) 4 times daily Child 40 kg and over and adult: 500 mg 4 times daily
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Streptococcal pharyngitis, scarlet fever: 10 days Diphtheria: 14 days
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Take between meals. Phenoxymethylpenicillin is also used in children for the prevention of pneumococcal infections in sickle cell disease and recurrence of acute rheumatic fever.
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– – Below 25 °C For the oral suspension (powder or reconstituted suspension): follow manufacturer’s instructions.
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10 to 15 mg/kg (max. 500 mg) 4 times daily
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500 mg 4 times daily
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