Drug reference
Priapism associated with alprostodil, if aspiration and lavage of the corpora are unsuccessful (alternative to adrenaline or metaraminol) ▶BY INTRACAVERNOSAL INJECTION ▶Adult: 100–200 micrograms every 5–10 minutes, dose to be administered using a 200 micrograms/mL solution; maximum 1 mg per course l UNLICENSED USE Use of phenylephrine hydrochloride injection in priapism is an unlicensed indication.
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Hypertension
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→Appendix 1: sympathomimetics, vasoconstrictor
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Angle closure glaucoma. anxiety. appetite decreased. arrhythmias. asthenia. confusion. dyspnoea. headache. hypertension. hypoxia. insomnia. nausea. palpitations. peripheral ischaemia. psychosis. tremor. urinary retention. vomiting
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For intracavernosal injection, if suitable strength of phenylephrine injection is not available, it may be specially prepared by diluting 0.1 mL of the phenylephrine 1% (10 mg/mL) injection to Genito-urinary system 5 mL with sodium chloride 0.9%.
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There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: solution for injection Solution for injection ▶Phenylephrine hydrochloride (Non-proprietary) Phenylephrine (as Phenylephrine hydrochloride) 50 microgram per 1 ml Phenylephrine 500micrograms/10ml solution for injection pre-filled syringes | 1 pre-filled disposable injection P £15.00 | 10 pre-filled disposable injection P £150.00 Phenylephrine hydrochloride 100 microgram per 1 ml Phenylephrine 1mg/10ml solution for injection ampoules | 10 ampoule P £40.00 Phenylephrine hydrochloride 10 mg per 1 ml Phenylephrine 10mg/1ml solution for injection ampoules | 10 ampoule P £99.12 Phenylephrine 10mg/1ml concentrate for solution for injection ampoules | 10 ampoule P £99.12 VASODILATORS › PERIPHERAL VASODILATORS
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100–200 micrograms every 5–10 minutes, dose
First-line fragment. Read the complete Indications and Dose section above.
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