Drug reference
Mydriasis ▶TO THE EYE ▶Child: Apply 1 drop, to be administered before procedure, a drop of proxymetacaine topical anaesthetic may be applied to the eye a few minutes before using phenylephrine to prevent stinging ▶Adult: Apply 1 drop, to be administered before procedure, then apply 1 drop after 60 minutes if required, a drop of topical anaesthetic may be applied to the eye a few minutes before using phenylephrine to prevent stinging
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10% strength eye drops in children. 10% strength eye drops in elderly. aneurysms. cardiovascular disease. hypertension. thyrotoxicosis
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Asthma. cerebral arteriosclerosis (in adults). corneal epithelial damage. darkly pigmented iris is more resistant to pupillary dilatation and caution should be exercised to avoid overdosage. diabetes (avoid eye drops in long standing diabetes). mydriasis can precipitate acute angle-closure glaucoma in a few patients, usually over 60 years and hypermetropic (long-sighted), who are pre- disposed to the condition because of a shallow anterior chamber. mydriasis can precipitate acute angle-closure glaucoma in the very few children who are predisposed to the condition because of a shallow anterior chamber. ocular hyperaemia. susceptibility to angle-closure glaucoma
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Although multi-dose phenylephrine eye drops commonly contain preservatives, preservative-free unit dose vials may be available.
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→Appendix 1: sympathomimetics, Eye vasoconstrictor
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Arrhythmias. conjunctivitis allergic. eye discomfort. hypertension. myocardial infarction (usually after use of 10% strength in patients with pre-existing cardiovascular disease). palpitations. periorbital pallor (in children). vision disorders
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Use only if potential benefit outweighs risk.
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Use only if potential benefit outweighs risk—no information available.
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There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: eye drops Eye drops EXCIPIENTS: May contain Disodium edetate, sodium metabisulfite ▶Phenylephrine hydrochloride (Bausch & Lomb UK Ltd) Phenylephrine hydrochloride 25 mg per 1 ml Minims phenylephrine hydrochloride 2.5% eye drops 0.5ml unit dose | 20 unit dose p £11.87 DT = £11.87 Phenylephrine hydrochloride 100 mg per 1 ml Minims phenylephrine hydrochloride 10% eye drops 0.5ml unit dose | 20 unit dose p £11.87 DT = £11.87
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Driving and skilled tasks Patients should be warned not to undertake skilled tasks (e.g. driving) until vision clears after mydriasis.
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Apply 1 drop, to be administered before
First-line fragment. Read the complete Indications and Dose section above.
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Apply 1 drop, to be administered before
First-line fragment. Read the complete Indications and Dose section above.
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