Therapeutic Action
Vitamin, anti-haemorrhagic
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Drug reference
Vitamin, anti-haemorrhagic
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Prophylaxis and treatment of haemorrhagic disease of the newborn
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May cause: allergic reactions, especially by IV route; haematoma at IM injection site. Pregnancy: no contra-indication Breast-feeding: no contra-indication
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2 mg ampoule (10 mg/ml, 0.2 ml), for oral administration, IM or slow IV injection
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Prophylaxis of haemorrhagic disease of the newborn By IM route, the day of birth: Neonate < 1.5 kg: 0.5 mg single dose Neonate ≥ 1.5 kg: 1 mg single dose Treatment of haemorrhagic disease of the newborn By IM or slow IV route: 1 mg every 8 hours if necessary, depending on clinical evolution and coagulation tests results
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Also comes in 10 mg ampoules (10 mg/ml, 1 ml) for use in adults only (treatment of haemorrhage due to antivitamin K agents, etc.) . Vitamin K is also used as prophylaxis for neonatal hypoprothrombinemia in mothers treated with 1 enzyme-inducing antituberculosis drugs (rifampicin, rifabutin) during pregnancy. Use 10 mg ampoules (10 mg/ml, 1 ml): administer 10 mg/day of vitamin K by oral route for 15 days before 1 birth. This maternal prevention does not change the need for IM administration of vitamin K in 1 neonates. Do not dilute or mix with other drugs in the same syringe. Storag – Below 25 °C
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0.5 mg single dose
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1 mg single dose
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