Names and pronunciation
(pye-oh-gli′ta-zone/met-for′min) Actoplus Met
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Drug reference
(pye-oh-gli′ta-zone/met-for′min) Actoplus Met
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Func. class.: Antidiabetic
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USES: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both pioglitazone and metformin is needed
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CONTRAINDICATIONS: Hypersensitivity to pioglitazone, metfor- min, or any component; established NYHA class III or IV HF, severe renal disease (eGFR <30 mL/min/1.73 m2); P metabolic acidosis, diabetic ketoacidosis
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DOSAGE AND ROUTES Diabetes mellitus, type 2. • Adult: PO Initial: Pioglitazone 15 mg/ metformin 500 mg bid or pioglitazone 15 mg/metformin 850 mg daily
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Available forms: Tabs 15/500, 15/850 mg
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• Adult: PO Initial: Pioglitazone 15 mg/ metformin 500 mg bid or pioglitazone 15 mg/metformin 850 mg daily
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