Drug reference

Prednisolone

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1249

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Drug Action

Prednisolone exerts predominantly glucocorticoid effects with minimal mineralocorticoid effects.

PDF page 1249

Indications And Dose

Local treatment of inflammation (short-term) ▶TO THE EYE ▶Child: Apply every 1–2 hours until controlled then reduce frequency ▶Adult: Apply every 1–2 hours until controlled then reduce frequency l UNLICENSED USE Pred Forte ® not licensed for use in children (age range not speciﬁed by manufacturer).

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Prescribing And Dispensing Information

Although multi-dose prednisolone eye drops commonly contain preservatives, preservative-free unit dose vials may be available.

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Safety

Interactions

→Appendix 1: corticosteroids

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Side Effects

Eye discomfort. taste altered. visual impairment

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Pregnancy

As it crosses the placenta 88% of prednisolone is inactivated.

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Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: eye drops Eye drops EXCIPIENTS: May contain Benzalkonium chloride, disodium edetate, polysorbates ▶Minims (Bausch & Lomb UK Ltd) Prednisolone sodium phosphate 5 mg per 1 ml Minims prednisolone sodium phosphate 0.5% eye drops 0.5ml unit dose | 20 unit dose P £12.25 DT = £12.25 ▶Pred Forte (Allergan Ltd) Prednisolone acetate 10 mg per 1 ml Pred Forte 1% eye drops | 5 ml P £1.82 DT = £1.82 | 10 ml P £3.66 DT = £3.66 Ear/eye drops solution EXCIPIENTS: May contain Benzalkonium chloride, disodium edetate ▶Prednisolone (Non-proprietary) Prednisolone sodium phosphate 5 mg per 1 ml Prednisolone sodium phosphate 0.5% ear/eye drops | 10 ml P £2.57 DT = £2.57 CORTICOSTEROIDS › CORTICOSTEROID COMBINATIONS WITH ANTI-INFECTIVES

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Dose text by age group

Child

Apply every 1–2 hours until controlled then

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1249

Adult

Apply every 1–2 hours until controlled then

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1249

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Prednisolone

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1249

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Drug Action

Prednisolone exerts predominantly glucocorticoid effects with minimal mineralocorticoid effects.

PDF page 1249

Indications And Dose

PDF page 1249

Prescribing And Dispensing Information

Although multi-dose prednisolone eye drops commonly contain preservatives, preservative-free unit dose vials may be available.

PDF page 1249

Safety

Interactions

→Appendix 1: corticosteroids

PDF page 1249

Side Effects

Eye discomfort. taste altered. visual impairment

PDF page 1249

Pregnancy

As it crosses the placenta 88% of prednisolone is inactivated.

PDF page 1249

Dose and formulations

Medicinal Forms

PDF page 1249

Dose text by age group

Child

Apply every 1–2 hours until controlled then

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1249

Adult

Apply every 1–2 hours until controlled then

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1249

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.